No registrations found.
ID
Source
Brief title
Health condition
Glaucoma and tinnitus
Sponsors and support
Intervention
Outcome measures
Primary outcome
Concentrations of amino acids which mark nitric oxide
production in glaucoma patients both with and without tinnitus.
Secondary outcome
N/A
Background summary
Low nitric oxide (NO) bioavailability and oxidative stress may be common
mechanisms behind glaucoma and tinnitus. NO itself diffuses quickly and is difficult to
measure, however, certain metabolites can be measured as biomarkers of NO production.
The aim of this study is to test these biomarkers of NO in glaucoma patients
both with and without tinnitus.
Study objective
The amino acids from the glaucoma patients will show a decrease in nitric oxide
bioavailability and there will be an increase in excitotoxicity markers in those with tinnitus.
Study design
Patients will come for one appointment only
Intervention
N/A
Inclusion criteria
50-70 years of age
diagnosed primary open angle glaucoma
written informed consent
Exclusion criteria
Since we are choosing patients based on inclusion criteria, we do not for see any reason to exclude a patient unless they no longer want to participate.
Design
Recruitment
IPD sharing statement
Plan description
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8329 |
| Other | UMCG Research Database : 202000047 |