No registrations found.
ID
Source
Brief title
Health condition
Atopic dermatitis of the face in children
Sponsors and support
Prof GL Marseglia
Pediatric Clinic Ospdale San Matteo
Intervention
Outcome measures
Primary outcome
EASI score (eczema, itch, infiltration,escoriation)
Secondary outcome
Investigator global assessement
Background summary
The hypotesis is that a cream containing rhamnosoft, nuiacinamide and isoleucine could be more efficacious.
Study objective
Isoleucine is an aminoacid showing in vitro efficacy in increasing keratinocytes to increase the production of Antimicrobial peptides (AMP)such as beta defensine. In AD there is a reduced production of AMP
Study design
Evaliation of EASI score (facial) at baseline
3 weeks
6 weeks (end of treatment)
Intervention
Cream containing rhamnosoft, niacinamide and Isoleucine
Standard emollient cream (glycerol)
Inclusion criteria
Children aged 1-12 years
Atopic Dermatitis mild to moderate
Presence of lesions on the Face
Exclusion criteria
Severe AD
Treatment with systemic anti-inflammatory drugs
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL3914 |
| NTR-old | NTR4084 |
| Other | : N/A |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |