No registrations found.
ID
Source
Brief title
Health condition
sensibility breast, sensibility abdomen, breast reconstruction, breast cancer, receptor
Sponsors and support
Maastricht University Medical Centre
Intervention
Outcome measures
Primary outcome
percentage of receptors responsible for the sensiblity in the skin.
Secondary outcome
The difference in percentage of receptors beteween breast, nipple, areola and abdomen.
Background summary
By taking biopsies of the skin of the breast and the abdomen we will analyze the difference in percentages of receptors responsible for the sensibility. This can be of great value for the expected results concerning the sensibility after a breast reconstruction.
Study objective
The percentage of receptors responsible for sensibility in the breast (and nipple) differ from the percentage of receptors in the abdominal skin.
Study design
biopsy during the operation.
Intervention
During the mastectomy 6 biopsies of 5mm will be taken of the skin that will be removed during the mastectomy.
During the abdominal surgery (DIEP, lowerbodylift, abdominoplasty) 2 biopsies of 5mm will be taken of the skin that will be removed during this surgery.
The biopsies will be analyzed and the percentage of receptors responsible for the sensbility in the skin will be compared.
Nadine Hillberg
Postbus 5500
Sittard-Geleen 6130 MB
The Netherlands
0031648531220
n.hillberg@zuyderland.nl
Nadine Hillberg
Postbus 5500
Sittard-Geleen 6130 MB
The Netherlands
0031648531220
n.hillberg@zuyderland.nl
Inclusion criteria
-female - Age of at least 18 years
- Mastery of the Dutch language in word and writing.
- Informed consent for participation in the research
- biopsy of the tissue is possible from the tissue that will be removed during a mastectomy or abdominal operation (lowerbodylift, DIEP or abdominoplasty)
Exclusion criteria
- clinical abnormalities are visible on the nipple
- Mastitis, ulcerations on the breast or a T4-tumor. r.
- Suspicion of M. Paget
- On imaging the tumor is located in less than 2cm distance of the nipple.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL7281 |
| NTR-old | NTR7514 |
| Other | : METCZ20180082 |