No registrations found.
ID
Source
Health condition
Peri-implantitis
Sponsors and support
Intervention
Outcome measures
Primary outcome
Percentage of sites with bleeding on probing (% sites BoP) was used as primary clinical outcome variable
Secondary outcome
Secondary clinical outcome variables were presence of plaque (% sites plaque), suppuration on probing (% sites SoP), mean PPD and radio-graphical marginal bone loss at baseline. Next to this microbiolical parameters were recorded.
Background summary
An effective intervention protocol for treatment of peri-implantitis is not yet available. The objective of this randomized, double-blinded controlled clinical trial was to assess the clinical, microbiological and radiographical effect of decontamination of the implant surface during surgical treatment of peri-implantitis using 35% phosphoric acid or sterile saline.
Study objective
Decontamination of the implant surface with 35% phosphoric acid during the surgical treatment of peri-implantitis does result in better clinical and microbiological outcome compared to sterile saline
Study design
- Baseline
- After 3 months
- After 12 months
Intervention
Peri-implant lesions were treated with resective surgical treatment consisting of apically repositioned flap, bone recontouring and surface debridement and decontamination. After mechanically cleaning, the implant surfaces were treated with 35% phosphoric etching gel
Department of Oral Sugery
P.O. Box 30001
G.M. Raghoebar
Groningen 9700 RB
The Netherlands
+31(0)50 3613186
g.m.raghoebar@kchir.umcg.nl
Department of Oral Sugery
P.O. Box 30001
G.M. Raghoebar
Groningen 9700 RB
The Netherlands
+31(0)50 3613186
g.m.raghoebar@kchir.umcg.nl
Inclusion criteria
Inclusion criteria were:
•≥ 18 years of age;
•at least one endosseous implant with clinical and radiographical signs of peri-implantitis;
•implants were in function for at least two years;
•capable of understanding and providing informed consent.
Exclusion criteria
•Contraindications for the surgical procedures;
•A history of local radiotherapy to the head and neck region;
•Pregnancy and lactation;
•Insuline-dependent diabetes;
•Systemic use of antibiotics during the last 3 months;
•Long-term use of anti-inflammatory drugs;
•Incapability of performing basal oral hygiene measures as a result of physical or mental disorders;
•Uncontrolled periodontitis (PPD > 5mm);
•Implants placed in skin grafted areas;
•Implants with bone loss due to other reasons than bacterial infection (e.g. loose screw, inadequate positioning of the implant);
•Implants with bone loss exceeding 2/3 of the length of the implant or implants with bone loss beyond the transverse openings in hollow implants;
•Implant mobility;
•Implants at which no position can be identified where proper probing measurements can be performed;
•Previous surgical treatment of the peri-implantitis lesions.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5046 |
| NTR-old | NTR5185 |
| Other | University Medical Center Groningen : METc2013.005 |
Summary results
de Waal YC, Raghoebar GM, Huddleston Slater JJ, Meijer HJ, Winkel EG, van Winkelhoff AJ. Implant decontamination during surgical peri-implantitis treatment: a randomized, double-blind, placebo-controlled trial. J Clin Periodontol. 2013;40:186-195.