No registrations found.
ID
Source
Brief title
Health condition
Stroke patients with unilateral spatial neglect
Sponsors and support
Intervention
Outcome measures
Primary outcome
Performance on a digitalised Star Cancellation Test
Secondary outcome
- Performance on a Computerised Visual Detection Task
- Performance on Line Bisection Task
- Performance on Baking Tray Task
Background summary
Hemispatial neglect is a common symptom in stroke patients and is marked by the inability to attend to the contralesional side of space. The standard cognitive training for neglect in the subacute phase of stroke is visual scanning training (VST). However, VST requires many sessions to have a long-lasting effect. Here, we aim to increase the effectiveness of VST by applying non-invasive brain stimulation, namely transcranial Alternating Current Stimulation (tACS), to the frontoparietal attention network in patients with neglect following subacute stroke.
Study objective
The application of dual site tACS during cognitive training ameliorates spatial neglect symptoms to a larger extent than the application of sham stimulation during cognitive training.
Study design
Unkwown
Intervention
We will combine an evidence based Visual Scanning Training with 40 minutes of (active or sham) dual site tACS at the theta (6 Hz) and gamma (80 Hz) frequencies. The intervention is administered 5 times a week for a duration of 2 weeks.
Inclusion criteria
• 30-80 years of age
• Subacute stroke (stroke occurred more than 2 weeks and less than 6 months ago; first or recurrent, ischemic or intracerebral haemorrhagic lesion)
• Diagnosed visuospatial neglect and/or spatial neglect symptoms (either left or right sided) on the basis of clinical judgement (i.e. by the cooperating clinical (neuro)psychologist).
• Sufficient comprehension and communication skills to benefit from training (based on clinical judgement)
Exclusion criteria
• Physically or mentally unable to participate (e.g. to perform the neglect training)
• Severe communicative disability, including aphasia
• Local scalp injuries
• Eczema on scalp or psoriasis
• (Neuro)psychiatric or neurodegenerative diseases including dementia, serious depression, multiple sclerosis, Parkinson’s disease, Huntington’s disease on the basis of clinical judgement (i.e. cooperating (neuro)psychologist)
• Current alcohol and/or drug abuse or a history of abuse within the last 6 months
• Pregnancy
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8145 |
| Other | METC : METC 19-081 |