No registrations found.
ID
Source
Brief title
Health condition
Clinical trial.
Sponsors and support
Meibergdreef 9
1100 DD
Amsterdam
Intervention
Outcome measures
Primary outcome
Asymptomatic and symptomatic catheter-related deep vein thrombosis proven by ultrasound or venography.
Secondary outcome
1. Catheter-related infections;
2. Bleeding complications.
Background summary
Double blind randomized controled trial to analyze the efficacy of nadroparin on catheter-related deep vein thrombosis in patients treated with high chemotherapy.
Study objective
Low dose nadroparin will prevent symptomatic and asymptomatic catheter-related deep vein thrombosis in patienten treated with high dose chemotherapy.
Study design
N/A
Intervention
Nadroparin SC 1 dd 2850 E versus placebo 0.3 ml SC during 21 days.
P.O. Box 22660
B.J. Biemond
Meibergdreef 9
Amsterdam 1100 DD
The Netherlands
+31 (0)20 5667391
b.j.biemond@amc.uva.nl
P.O. Box 22660
B.J. Biemond
Meibergdreef 9
Amsterdam 1100 DD
The Netherlands
+31 (0)20 5667391
b.j.biemond@amc.uva.nl
Inclusion criteria
1. Central venous catheter;
2. Indication for high dose chemotherapy
(AML, ALL, MDS-RAEB, MM);
3. Informed consent.
Exclusion criteria
1. Current anticoagulant therapy;
2. Allergy for contrastmedia;
3. AML-M3 (promyelocytic leukemia);
4. Bleeding tendency;
5. Renal failure.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL611 |
| NTR-old | NTR669 |
| Other | : N/A |
| ISRCTN | ISRCTN29686154 |