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ID
Source
Brief title
Health condition
Fetal blood sampling during labor due to a suspicion of fetal distress
Sponsors and support
Intervention
Outcome measures
Primary outcome
Negative predictive value and positive predictive value of fetal scalp lactate on neonatal acidosis. Neonatal acidosis is associated with arterial umbilical cord pH <7.10 and base deficit >-12, Apgar scores <7 after 5 minutes and admission to the neonatal intensive care unit.
Secondary outcome
NPV and PPV of fetal scalp lactate on composite outcomes (defined as either arterial umbilical cord pH <7.10 and base deficit >-12 or Apgar scores <7 after 5 minutes or admission to the neonatal intensive care unit).
PPV and NPV of fetal scalp lactat on interventionrate
Discrepancies between fetal scalp lactate and fetal scalp pH measurements
Failure rates of fetal scalp lactate, fetal scalp pH and umbilical cord pH measurements
CTG pattern at time of fetal blood sampling
Fetal scalp lactate pattern in case of repeated measurements
Background summary
In this retrospective cohort study, we would like to determine the negative and positive predictive values of fetal scalp lactate measurements in case of non-reassuring heart rate patterns on adverse neonatal outcomes. In our cohortstudy, both fetal scalp pH and fetal scalp lactate measurements are sampled at the same time.
Study objective
Fetal scalp lactate measurement is equally good or superior than fetal scalp pH measurements during labor in case of nonreassuring fetal heart rate patterns in predicting adverse neonatal outcomes.
Study design
Start of study: 15-1-2020
Intervention
Fetal Blood sampling
Inclusion criteria
Women in labor with fetal blood sampling during labor
Giving birth in our centre (Máxima MC)
Singleton fetus
Cephalic presentation
Exclusion criteria
Maternale age <18 years old
Gestational age <34+0 weeks
Multiple pregnancy
Suspicion of fetal clotting disorder
Maternal infection like HIV or hepatitis
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8305 |
| Other | METC Máxima MC : N20.006 |