No registrations found.
ID
Source
Brief title
Health condition
MRSA control in surgery.
Sponsors and support
Intervention
Outcome measures
Primary outcome
Number of patients with nosocomial MRSA infection acquired in surgery, expressed as incidence per 1000 patient-days
Secondary outcome
1. Nosocomial MRSA acquisition rate (expressed as the rate of new MRSA cases detected by any type of clinical isolate in previously MRSA-free patients per 1000 patient-days);
2. The rate of surgical site infections (per 100 procedures) and other site-specific infections caused by MRSA.
Background summary
Background:
Carriage of methicillin-resistant Staphylococcus aureus (MRSA) places patients at risk for MRSA infection. Experts and politicians have repeatedly called for widespread admission screening to reduce nosocomial MRSA infection.
Objectives:
To determine the effect of an early MRSA detection strategy on nosocomial MRSA infections in a cohort of 21’754 surgical patients at a large teaching hospital.
Methods:
We carried out a prospective, interventional cohort study using a cross-over design to compare two different MRSA control strategies (rapid screening plus standard control versus standard control only). Twelve surgical wards were assigned to 2 study groups and enrolled according to a pre-specified agenda, encompassing 4 study phases. Patients admitted for >24 h were screened upon admission by quick, multiplex PCR. MRSA infections acquired in surgery were the primary outcome measure.
Study objective
To determine the effect of an early MRSA detection strategy on nosocomial MRSA infections in a cohort of surgical patients at a large teaching hospital.
Study design
N/A
Intervention
Rapid MRSA screening.
Infection Control Program
Stephan Harbarth
24, rue Micheli-du-Crest
Geneva 1211
Switzerland
+41 22 372 3357
stephan.harbarth@hcuge.ch
Infection Control Program
Stephan Harbarth
24, rue Micheli-du-Crest
Geneva 1211
Switzerland
+41 22 372 3357
stephan.harbarth@hcuge.ch
Inclusion criteria
All patients admitted to the surgical department for >24 hours.
Exclusion criteria
Ambulatory surgery.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1012 |
| NTR-old | NTR1041 |
| Other | : |
| ISRCTN | ISRCTN06603006 |