No registrations found.
ID
Source
Brief title
Health condition
Asthma
Sponsors and support
Intervention
Outcome measures
Primary outcome
- mental health status before and during a pandemic
- number of respiratory tract infections and asthma exacerbations before and during a pandemic
Secondary outcome
- Quality of life and physical activity for asthma patients during a pandemic
- Occurrence of proven COVID-19 in asthma patients
- Occurrence of missed GP/first aid visits during a pandemic
Background summary
The current prevalence of COVID-19 pandemic in The Netherlands again puts patients with respiratory disorders at risk for a severe disease and death. COVID-19 is very contagious and has spread very rapidly across the world. The virus can cause symptoms ranging from mild to critical. Mild symptoms, which occur in 81% of all cases, include mild fever, nasal congestion, (dry) cough, sore throat, malaise and headache. However, in 14% of all cases, the virus causes more severe symptoms ranging from severe dyspnoea to tachypnea and hypoxia. Besides this, 5% of all cases reach an even more critical stage which might result in death due to respiratory failure, septic shock and/or multiple organ dysfunction. Since COVID-19 can cause a viral lung infection, with a pneumonia superinfection, asthma patients are at risk for having a more severe clinical picture and a worse disease outcome. It is to be expected that asthmatic patients experience more stress and anxiety for COVID-19 during this pandemic period compared to a recent period before the COVID-19 pandemic. Also, first aid posts and general practitioners report a decrease in patients that ask for help. This might be due to: 1) social distancing and therefore a reduced infection transmission ,or 2) by avoidance from patients due to COVID-19 fear or the expectation of overcrowding in these places.
Study objective
Asthma patients experience more anxiety during COVID-19 compared to a stable timepoint in the past.
Study design
Primary & Secondary endpoints:
T0: Study visit for Grandma / Breathe study in spring 2018 / 2019 including:
- HADS, FSS, ACQ, AQLQ;
- Number of respiratory tract infections and asthma exacerbations in the past 3 months.
T12: During COVID-19 pandemic in The Netherlands:
- Surveydata including a COVID-19 likert scale and questions on health care need.
- HADS, FSS, ACQ, AQLQ
- Number of respiratory tract infections and asthma exacerbations in the past 3 months
Intervention
Surveys
Inclusion criteria
Included in either Breathe (NL5752) or Grandma (NCT03278561) study.
Exclusion criteria
- Did not agree to be asked for future research.
- Dropped out of Breathe study within 6 months after study initiation
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
NTR-new | NL8576 |
Other | Advisory Commity Franciscus Gasthuis & Vlietland : 2020-049 |