No registrations found.
ID
Source
Brief title
Sponsors and support
Intervention
Outcome measures
Primary outcome
Change of time constant of O2 onset or recovery kinetics > 10 sec.
Secondary outcome
1. Change of peak VO2;
2. Quality of Life.
Background summary
Oxygen uptake kinetics provide objective information on the ability to adapt to and recover from exercise that is indicative of daily life in patients with chronic heart failure. Therefore this parameter is potentially useful for measuring effects of exercise training in these patients. The main goal of this study is to determine the effects of exercise training on O2 onset and recovery kinetics in patients with chronic heart failure.
Study objective
The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure effects of exercise training in patients with chronic heart failure.
Study design
N/A
Intervention
Exercise training (12 weeks) versus standard care.
P.O. Box 7777
Hareld M.C. Kemps
Veldhoven 5500 MB
The Netherlands
+31 (0)40 8888620
H.Kemps@wxs.nl
P.O. Box 7777
Hareld M.C. Kemps
Veldhoven 5500 MB
The Netherlands
+31 (0)40 8888620
H.Kemps@wxs.nl
Inclusion criteria
Stable CHF (NYHA class II-III and echocardiographical ejection fraction <= 40%) attributed to idiopathic dilated cardiomyopathy or ischemic heart disease due to myocardial infarction.
Exclusion criteria
1. Myocardial infarction / unstable angina pectoris in previous 3 months;
2. Atrial fbrillation / flutter;
3. COPD (Tiffenau index < 60%).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL576 |
| NTR-old | NTR632 |
| Other | : N/A |
| ISRCTN | ISRCTN66318889 |