No registrations found.
ID
Source
Brief title
Health condition
decreased left ventricular function, cardioverter defribrillator, echocardiography
Sponsors and support
Intervention
Outcome measures
Primary outcome
LV systolic function and contractility will be assessed.
Secondary outcome
Postoperative problems, such as nausea, vomiting, changes of haemodynamics 20 % beyond baseline measurements, or hypoxia will be reported. Also postoperative nausea and vomiting, shivering dizziness, confusion etc. are stated as adverse events.
Background summary
The study is designed to elucidate the differences in haemodynamics and effects on myocardial function in severely depressed left ventricular function, both in Xenon and Desflurane anesthetised patients undergoing cardioverter defribrillator implantation.
Study objective
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
Study design
After induction of anesthesia and after hemodynamic stabilisation after the start of the anesthetic.
Intervention
Xenon versus Desflurane anesthesia monitored by TOE.
Veerle Mossevelde, van
Brussels 1090
The Netherlands
+32 (0)2 4763134
veerle.vanmossevelde@uzbrussel.be
Veerle Mossevelde, van
Brussels 1090
The Netherlands
+32 (0)2 4763134
veerle.vanmossevelde@uzbrussel.be
Inclusion criteria
1. Patients scheduled for internal cardioverter defibrillator implantation;
2. A preoperative left ventricular ejection fraction < .4, as assessed on echocardiography or left ventricular angiography;
3. Age > 17 y;
4. Planned surgery < 2 h.
Exclusion criteria
1. Patients with COPD, myocardial infarction < 3 m before surgery;
2. Withdrawal from the study is performed whenever a serious adverse event (e.g. major bleeding, shock or death) occurs.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL2762 |
| NTR-old | NTR2901 |
| Other | MEC UZ Brussel : 2011/025 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |