No registrations found.
ID
Source
Health condition
Post-mortem radiology. Whole-body MRI. Whole-boy CT. Whole-body imaging. CT-guided biopsy. MIA: diagnostic performance. Image-guided biopsy. Stereotactic brain biopsy. Conventional autopsy. Alternative autopsy.
Sponsors and support
Stichting Coolsingel
KWF kankerbestrijding
Intervention
Outcome measures
Primary outcome
Agreement between MIA and CA for cause of death and sensitivity and specificity of major and overall findings
Secondary outcome
- Comparing CA and MIA of the brain.
- Estimating the amount of information lost by MIA, compared to the CA and finding out if the expected increase of autopsies performed compensates for this loss.
- Comparing costs of the MIA versus CA.
Study objective
MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
Study design
Not appicable
Intervention
We performed MIA followed by CA the following day. Both the MIA investigators and CA pathologists who performed the autopsy received the same clinical information and were blinded to each other's findings.
Inclusion criteria
Deceased adult patients, written informed consent from next of kin, availability of imaging equipments and technologists
Exclusion criteria
forensic causes of death, known or suspected “high-risk” infected cadavers (hepatitis C, human immunodeficiency virus, tuberculosis), open abdominal wounds and body size too large for imaging equipment.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
NTR-new | NL4732 |
NTR-old | NTR5072 |
Other | : MEC-2011-055 |