No registrations found.
ID
Source
Brief title
Health condition
Healthy adults
Sponsors and support
Intervention
Outcome measures
Primary outcome
Blood glucose response
Secondary outcome
Safety and gastrointestinal tolerance
Background summary
In this study, the effect of 5 different fibre mixtures on glucose response is assessed. In addition, safety and gastrointestinal tolerance will be monitored. Thirty-five healthy volunteers will consume these 5 study products in a randomized cross-over manner (>48 hours between each session).
Whole grain cereal had a lower glucose peak value compared to rice cereal. The glycaemic response overall (AUC) did not differ between the five different fibre mixtures. No safety and tolerance issues regarding the consumption of the five fibre mixtures were identified during the study.
Study objective
The addition of a specific fibre mixture to a breakfast cereal will impact the blood glucose response.
Study design
acute changes in blood glucose levels measured 8 times over a period of 3 hours.
Intervention
Duration of intervention: approximately 3 weeks
Intervention: 5 different breakfast cereals will be consumed by subjects in a randomized, cross-over design. Duration of intervention: approximately 3 weeks
Clinical Studies Platform
Uppsalalaan 12
Maaike Hofman
Utrecht 3584 CT
The Netherlands
+31 (0)302095000
maaike.hofman@danone.com
Clinical Studies Platform
Uppsalalaan 12
Maaike Hofman
Utrecht 3584 CT
The Netherlands
+31 (0)302095000
maaike.hofman@danone.com
Inclusion criteria
Age 18-30 years
Male or female volunteers
BMI between 18-25
Diagnosis: self- assessed as healthy, confirmed by medical questionnaire during screening
Provide written informed consent
Non-smokers
Exclusion criteria
Diabetes Mellitus
History of heart disease and/or high blood pressure
Individuals who have any food intolerance or allergic reactions
Individuals currently taking regular medication or nutritional supplements (incl. vitamins) other than the contraceptive pill.
Having participated in a drug or dietary intervention trial within the last 2 months prior to first test session
Non-native English speakers
Individuals with a history of neurological or psychiatric illness
Pregnant or lactating females
Frequent breakfast skippers
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4132 |
| NTR-old | NTR4285 |
| Other | : DGS.1.C/B/0 / Nutricia Research |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |