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ID
Source
Brief title
Health condition
Early glottic cancer, T2 glottic carcinoma, voice outcome, radiotherapy, radiation therapy, voice quality, voice function, quality of life
Sponsors and support
Intervention
Outcome measures
Primary outcome
Voice outcome
Voice quality (Voice Handicap Index questionnaire)
Voice function (maximum phonation time, fundamental frequency, dynamic range and perceptual evaluation)
Secondary outcome
Swallowing (MDADI)
Quality of Life (EORTC QLQ-C30 / HN35)
Background summary
Introduction: Several studies report functional outcomes (voice function, voice quality, quality of life, and swallowing function) after treatment with radiotherapy for T1 glottic carcinoma. Patients with T1 glottic tumors show the same results, regarding the functional outcomes, after radiotherapy of transoral laser microsurgery (TLM). However, for patients with T2 tumors treated with radiotherapy, these results are not frequently decribed. Due to the lack of these data, we would like to perform a study to investigate the long-term functional outcomes of patienst treated with radiotherapy. The objective of this study is to determine the functional outcomes (voice function, voice quality, quality of life and swallowing function) in patients who were treated with radiotherapy for a T2 glottic tumor between 2008 and 2016.
Method: a crossectionals study will be performed, where patients will be asked to fill in two questionnaaires. Furthermore, voice analysis will be performed in the outpatient clinics.
Study objective
We think that patients that were treated for a T2 glottic carcinoma with radiotherapy have mild-to moderate dysphonic voices, no problems with swallowing and a good quality of life.
Study design
1 time
Intervention
Questionnaires and recordings from the speech
Inclusion criteria
Patients treated with RT between 2008 and 2016 because of a T2 glottic carcinoma
Exclusion criteria
Patients with recurrent disease
Patients that are not able to read or speak Dutch
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL7480 |
| NTR-old | NTR7722 |
| CCMO | NL66191.058.18 |
| OMON | NL-OMON45759 |