No registrations found.
ID
Source
Brief title
Health condition
healthy preterm and term neonates which are growing well
relatief gezonde premature en a terme neonaten die een goede groei vertonen
Sponsors and support
Intervention
Outcome measures
Primary outcome
Requirement of the 9 essential amino acids determined by the breakpoint.
Secondary outcome
1. Length of adaptation time;
2. validation of the breath sampling compared to urine and blood sampling.
Study objective
The current estimations of the essential amino acids in neonates are inadequate. We hypothese these are too low.
Study design
On the studyday breath sampling at start of the study and at isotopic plateau every 15 minutes.
Intervention
Indicator Amino Acid Oxidation(IAAO).
Method: In short:
stable isotope by nasogastric tube
test essential amino acid in wide range of intake for 24 hours adaptation and 8 hours on study day.
Breath sampling for labelled CO2.
P.O. Box 2060
J.B. Goudoever, van
Rotterdam 3000 CB
The Netherlands
+31 (0)10 4636363
j.vangoudoever@erasmusmc.nl
P.O. Box 2060
J.B. Goudoever, van
Rotterdam 3000 CB
The Netherlands
+31 (0)10 4636363
j.vangoudoever@erasmusmc.nl
Inclusion criteria
Preterm: GA 28-36 weeks, BW< 2200 g, growth > 10 g/kg/d over the last 5 days.
Term: GA 37-42 weeks, BW > 2500 g, growth > 5 g/kg/d over the last 5 days.
Exclusion criteria
1. Gastro-intestinal pathology;
2. sepsis;
3. syndromes;
4. no informed consent.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1517 |
| NTR-old | NTR1588 |
| Other | : 2007-392 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |