No registrations found.
ID
Source
Brief title
Health condition
Megablaas, megacystis, LUTO (Lower Urinary Tract Obstructions), urethrale kleppen, urethra atresie, Urinewegobstructie
Sponsors and support
Intervention
Outcome measures
Primary outcome
Construction of reference curves for fetal bladder diameters and volume in the second and third trimester of pregnancy. .
Secondary outcome
The variation in the dimensions of renal pelvis in relation to the degree of bladder filling in healthy fetuses compared to 20 cases with mild pielectasy (defined as an antero-posterior renal pelvis between 5 and 10 mm) will be investigated. Moreover, we will prospectively validate both the cut-off of bladder enlargement derived from this study in 20 cases of megacystis diagnosed in subsequent years
Study design
- Recruitment process: December 2015/January 2016
- Data collection: February - May 2016
- Data Analysis: May - August 2016
Intervention
None
Inclusion criteria
Physiological singleton pregnancy in healthy women aged 18 or older, carrying a fetus without structural anomalies and capable of reading the Dutch language will be recruited at the dating scan (10-14 weeks).
Moreover twenty cases referred to our Fetal Unit for fetal mild pyelectasy, defined as an anteroposterior diameter of renal pelvis between 5-10 mm, will be included in the study.
Exclusion criteria
Incapacitated adults, maternal disease that are likely to affect the fetal growth (hypertension requiring therapy, diabetes mellitus), multiple pregnancies, the presence of fetal malformation, abnormal karyotype or any other disease at birth.
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5382 |
| NTR-old | NTR5483 |
| CCMO | NL54636.042.15 |
| OMON | NL-OMON42511 |