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ID
Source
Brief title
Health condition
Critical Illness
Sponsors and support
Intervention
Outcome measures
Primary outcome
To compare resting energy expenditure (REE), measured by indirect calorimetry, during ICU stay and post-ICU hospital stay.
Secondary outcome
To compare VCO2, VO2 and respiratory quotient (RQ), measured by the QNRG indirect calorimeter during ICU and post-ICU hospital stay. To compare REE measured by QNRG with the calculated REE using the VCO2-method and several other predictive equations. To associate REE and physical performance using the CPAx-score at the ICU- and hospital discharge.
Background summary
Single center prospective cohort study to compare the resting energy expenditure (REE), measured by the QNRG indirect calorimeter, during ICU stay and post-ICU hospital stay.
Study objective
During the convalescence phase of critical illness patients will enter an anabolic phase in which REE increases and there is a subsequent increased nutritional need.
Study design
IC measurements upon admission and once per 72 hours in ICU and the first week post ICU discharge and once a week until hospital discharge, thereafter.
Inclusion criteria
Admitted to the ICU of the ZGV hospital aged 18 and above, endotracheally mechanically ventilated, expected to be in ICU for more than 48 hours, expected to be in the general ward after ICU discharge.
Exclusion criteria
Fraction of inspired oxygen >0.7, PEEP>12 cm H2O, air leaks through tubes/cuffs and/or chest drains, pneumothorax, tracheaoesophageal fistulae or subcutaneous emphysema, unavailability of the QNRG metabolic monitor, peritoneal or hemodialysis or hemofiltration up to 4 hours before/after a session or during CRRT, expected to be transferred.
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8907 |
| Other | ZGV BCWO : 2002-007 |