No registrations found.
ID
Source
Brief title
Health condition
Congenital heart disease, ductus arteriosus, near-infrared spectroscopy, Doppler flow profiles, general movements, Prechtl's method, neurological outcome, neonate
Congenitale hartafwijkingen, ductus arteriosus, near-infrared spectroscopy, Doppler flow profielen, general movements, Prechtl's methode, neurologische ontwikkeling, neonaat
Sponsors and support
Intervention
Outcome measures
Primary outcome
General movements (GMs) according to Prechtl's method
Secondary outcome
Multisite near-infrared spectroscopy (NIRS)
Antenatal doppler flow profiles
Background summary
Infants with congenital heart disease are at risk of developing brain damage. This study is designed to gain more insight into the timing of brain damage via non-invasive clinical tools such as antenatal Doppler flow profiles, multisite near-infrared spectroscopy and general movements according to Prechtl's method.
Study objective
The objective of the study is to gain more insight into brain damage in infants with congenital heart disease. We hypothesize that infants with congenital heart disease are at risk of developing brain damage during early life or even before birth.
Study design
From diagnosis before birth to an age of three months.
GMs: age of seven days and age of three months
NIRS: day 1-7 after birth, during and after corrective surgery
Antenatal Doppler flow profiles: every 4 weeks after diagnosis
Intervention
none
kinderarts-neonatoloog, afdeling neonatologie
Beatrix Kinderziekenhuis, UMC Groningen
Huispostcode: CA 51
Hanzeplein 1
Postbus 30001
Groningen 9700 RB
The Netherlands
050-3614215
e.kooi@umcg.nl
kinderarts-neonatoloog, afdeling neonatologie
Beatrix Kinderziekenhuis, UMC Groningen
Huispostcode: CA 51
Hanzeplein 1
Postbus 30001
Groningen 9700 RB
The Netherlands
050-3614215
e.kooi@umcg.nl
Inclusion criteria
A cardiac anomaly on ultrasound before birth
Admission to the NICU after birth
Exclusion criteria
Premature birth before a gestational age of 36 weeks
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5101 |
| NTR-old | NTR5233 |
| CCMO | NL45567.042.14 |
| OMON | NL-OMON40142 |