No registrations found.
ID
Source
Brief title
Health condition
Acute Coronary Syndrome, Preventive cardiology, Secondary Prevention of Cardiovasculair disease, Nurse Specialists
Acuut coronair syndroom, Preventieve Cardiologie, Secundaire Preventie van hart- en vaatziekten, Gespecialiceerde verpleegkundigen
Sponsors and support
Department of Cardiology
F3-236
Academic Medical Center
P.O. Box 22660
1100 DD Amsterdam
The Netherlands
phone +31 20 5666952
fax +31 20 5669747
Email r.j.peters@amc.uva.nl
AstraZeneca, The Netherlands
Intervention
Outcome measures
Primary outcome
Copenhagen Risk score at 12 months follow-up.
Secondary outcome
1. Smoking status
2. Exercise status
3. Body Mass Index
4. Waist-to-hip ratio
5. Blood pressure
-Systolic blood pressure
-Diastolic blood pressure
6. Glucose parameters
-HbA1c
-Fasting glucose
7. Lipid profile
-Total cholesterol
-HDL
-LDL
-Triglycerids
8. Change in Diabetes status
Risk scores:
- Copenhagen Risk score
(at 6 months)
- Europa-score26
- PROCAM-score27
- Euroscore28
- SF-36
- MacNew
Background summary
Rationale: Treatments for secondary prevention of clinical events in patients with coronary artery disease are currently sub-optimally implemented. We hypothesize that a 6 month outpatient counselling and treatment course led by a nurse, in addition to usual care, reduces the risk of recurrent clinical events compared to usual care alone.
Objective:
Primary objective: To quantify the impact of outpatient nurse-led prevention clinics on the risk of future clinical events as calculated by the Copenhagen Risk score in patients with symptomatic coronary artery disease.
Study population: Patients aged 18-80 years who have been hospitalised less than 8 weeks before inclusion for an acute coronary syndrome.
Intervention: Intervention group is seen up to 4 times in 6 months following occurrence of acute coronary syndrome at a nurse-led outpatient clinic in addition to usual. Control group receives usual care only.
Main study parameters: The following parameters (and change herein) are compared at baseline, at 6 months and at 12 months after inclusion in study in both study groups:
1. Copenhagen Risk score
2. Smoking status
3. Exercise status
4. Body Mass Index
5. Waist circumference
6. Systolic blood pressure
7. Diastolic blood pressure
8. Diabetes status, fasting glucose, HbA1c levels
9. Total cholesterol, HDL, LDL, Triglycerides
Study objective
A 6 month outpatient counselling and treatment course by a nurse (in addition to usual care) reduces the risk of recurrent clinical events compared to usual care alone
Study design
Baseline
follow-up 6 months
follow-up 12 months
Intervention
Intervention group is seen up to 4 times in 6 months following occurrence of acute coronary syndrome at a nurse-led outpatient clinic in addition to usual care. The nurse-led outpatient clinic focuses on lifestyle, established cardiovascular risk factors and medication adherence.
Harald Thune Jørstad
Meibergdreef 9
P.O. Box 22660
Amsterdam 1100 DD
The Netherlands
+31 (0)20 5666837
h.t.jorstad@amc.uva.nl
Harald Thune Jørstad
Meibergdreef 9
P.O. Box 22660
Amsterdam 1100 DD
The Netherlands
+31 (0)20 5666837
h.t.jorstad@amc.uva.nl
Inclusion criteria
Patients between 18-80 years hospitalised less than 8 weeks before inclusion for an acute coronary syndrome, either unstable angina or acute myocardial infarction, will be included
Exclusion criteria
Patients will be excluded if clinic visits are not feasible, if not available for follow-up, if surgery, percutaneous coronary intervention or other interventions are expected within 8 weeks, if life expectancy is considered limited, if previously enrolled in NLPC or if NYHA class 3 or 4 from heart failure.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1244 |
| NTR-old | NTR1290 |
| Other | MEC : 06/109 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |