No registrations found.
ID
Source
Brief title
Health condition
depression
Sponsors and support
Intervention
Outcome measures
Primary outcome
Depression.
Secondary outcome
1. Changes in anxiety;
2. Autonomic changes;
3. Changes in the emotioneal attention, in the emotional memory en in de emotional recognition;
4. Biochemical changes;
5. Changes in the EEG.
Background summary
Subjects received rTMS daily on 10 consecutive weekdays (five sessions per week), during 20 minutes per session. .
During the rTMS session, the coil was centered flat over the right parietal cortex.
We follow the patient during 12 weeks after the 2 weeks of tms (follow-up period) to measure the depression with different rating scales.
Study objective
rTMS has a positive effect in the treatment of depression.
Study design
N/A
Intervention
REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION daily on 10 consecutive weekdays (five sessions per week), during 20 minutes per session.
Jan Tooropstraat 164
J. Riet, van der
Jan Tooropstraat 164
Amsterdam 1016 AE
The Netherlands
+31 (0)20 5108562
Jan Tooropstraat 164
J. Riet, van der
Jan Tooropstraat 164
Amsterdam 1016 AE
The Netherlands
+31 (0)20 5108562
Inclusion criteria
In and outpatients aged between 16 and 65 who met DSM-IV criteria for major depressive episode, and who had a score of 25 or higher on the 10-item Montgomery Asberg Depression Rating Scale (MADRS) were included.
Exclusion criteria
Exclusion criteria were a history of epilepsy and any other medical disorder that should preclude the administration of rTMS.
Only SSRI's, Mirtazapine and Promethazine as psychotropic medication was accepted if the dosage of antidepressive medication had not been changed for 6 weeks, and if the dosage of Promethazine had not been changed for 2 weeks prior to inclusion.
Antidepressive medication had to remain stable during the 14 weeks of the study.
Furthermore: schizofrenic disorder, a piece if metal in the brain, pacemaker and left-handed patients.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL187 |
| NTR-old | NTR224 |
| Other | : CCMO03.3741/SH/P03.1231L |
| ISRCTN | ISRCTN13548185 |