No registrations found.
ID
Source
Brief title
Sponsors and support
Intervention
Outcome measures
Primary outcome
Length of hospital stay.
Secondary outcome
1. Postoperative complications;
2. Time to restoration of gastric functions
and normal diet.
Background summary
Background:
Intravenous fluid administration after abdominal surgery is an essential, but variable part of postoperative care. The optimum suppletion volume after abdominal surgery is unknown. In colorectal surgery a restrictive fluid regime was found to reduce complications. We investigated the benefits of a restrictive postoperative intravenous fluid management in patients undergoing elective abdominal surgery.
Methods:
In a triple-blinded trial we randomly allocated patients undergoing elective abdominal surgery to a restrictive postoperative regime of 1,5 litre intravenous fluid/24h vs. 2,5 litre/24h, which was standard hospital practice. Primary outcome measure was length of hospital stay (LOS), secondary measures were postoperative complications and time to restoration of gastric functions and normal diet.
Study objective
A restrictive fluid regimen is beneficial for postoperative recovey after abdominal surgery, as to hospital stay and postoperative complications.
Study design
N/A
Intervention
1,5 litre intravenous fluid/24h vs. 2,5 litre/24h.
P.O. Box 22660
H. Vermeulen
Meibergdreef 9
Amsterdam 1100 DD
The Netherlands
H.Vermeulen@amc.uva.nl
P.O. Box 22660
H. Vermeulen
Meibergdreef 9
Amsterdam 1100 DD
The Netherlands
H.Vermeulen@amc.uva.nl
Inclusion criteria
1. Abdominal surgery;
2. Age > 18;
3. ASA I-III;
4. Understanding the Dutch language;
5. Signed informed consent.
Exclusion criteria
1. Cardiac diseases (NYHA > III en CCS > III);
2. Contraindications for epidural analgesia;
3. Presence of diabetes mellitus;
4. Planned for liver or oesophageal surgery;
5. Participating in another trial;
and/or anticipated postoperative stay in the Intensive Care Unit.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL588 |
| NTR-old | NTR644 |
| Other | : N/A |
| ISRCTN | ISRCTN16719551 |