No registrations found.
ID
Source
Brief title
Health condition
cognitive behaviour therapy (CBT), n=75
interpersonal therapy (IPT), n=75
8-week waiting list, n=30
Sponsors and support
Academic Riagg Maastricht
Intervention
Outcome measures
Primary outcome
Depressive relapse/recurrence in the course of 24 months.
Secondary outcome
1. Severity of depression (BDI);
2. Psychological problems;
3. Health care consumption;
4. Explicit and implicit mechanism of change measures.
Background summary
Although psychotherapy and antidepressants seem to help initially, many depressed patients suffer from relapse and recurrence. Recent findings suggest cognitive behaviour therapy (CBT) may reduce that risk in the long-term, but the mechanisms of change that prevent relapse and recurrence are still unknown. We will be the first to study the effectiveness of CBT compared to interpersonal therapy (IPT) for residual depression after initial treatment (reduction of symptoms; prevention of relapse and recurrence) and the underlying mechanisms of change (explicit and implicit measures). Participants will partly be recruited from an ongoing treatment study in primary care. These patients with residual depression will be offered psychotherapy (CBT or IPT) at our clinical site.
Study objective
Are CBT and IPT following initial treatment effective interventions that prevent relapse of recurrence of depression in the long-term? What are the mechanisms of change in CBT and IPT?
Intervention
Cognitive behaviour therapy (CBT), N=75;
Interpersonal therapy (IPT), N=75
8-week waiting list, N=30.
CBT= max. 20 sessions
IPT= max. 20 sessions
All interventions are delivered by qualified therapists under supervision at the Academic Riagg Maastricht.
Lotte Lemmens
Maastricht University, Faculty of Psychology and Neuroscience, Department of Clinical Psychological Science
Maastricht 6200 MD
The Netherlands
+31 (0)43 3881874
Lotte.Lemmens@maastrichtuniversity.nl
Lotte Lemmens
Maastricht University, Faculty of Psychology and Neuroscience, Department of Clinical Psychological Science
Maastricht 6200 MD
The Netherlands
+31 (0)43 3881874
Lotte.Lemmens@maastrichtuniversity.nl
Inclusion criteria
1. One or more episodes of MDD in past two years;
2. Initial treatment for depressive symptoms;
3. Residual symptoms of depression (BDI>=10).
Exclusion criteria
1. Chronic depression;
2. Concurrent treatment for depression;
3. Severe co-morbidity;
4. Medical conditions that explain depressive symptoms.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL825 |
| NTR-old | NTR838 |
| Other | : N/A |
| ISRCTN | ISRCTN67561918 |