No registrations found.
ID
Source
Brief title
Health condition
Yellow fever. Long term induced seroprotection after primary yellow fever vaccination.
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. Geometric mean titer (GMT) of YF neutralizing antibodies.
2. Percentage of participants with seroprotection.
Secondary outcome
None
Background summary
In this follow-up study we compare the yellow fever (YF) neutralizing antibodies 10 years after YF primary vaccination between elderly travellers (now 70 years or older) and younger controls.
Study objective
Elderly travellers have lower neutralizing antibody titers, ten years after yellow fever primary vaccination.
Study design
One time point (ten years after the initial trial, after primary yellow fever vaccination).
Intervention
Blood drawing (one blood sample).
Inclusion criteria
The study aims to include all participants of a prospective controlled cohort study conducted in 2008-2009, investigating the immune response after primary yellow fever vaccination.
Exclusion criteria
Booster yellow fever vaccination after the initial trial.
Design
Recruitment
IPD sharing statement
Plan description
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8079 |
| Other | METC LUMC : P19.037 |