No registrations found.
ID
Source
Brief title
Health condition
Age, thermoregulation, skin blood flow, temperature, hysteresis
Sponsors and support
Universiteitssingel 50,
6229ER Maastricht,
+31 43 388 4260,
b.kingma@hb.unimaas.nl
Intervention
Outcome measures
Primary outcome
1. Heat loss (W);
2. Heat content (J/m^3).
Secondary outcome
N/A
Background summary
In general elderly are predisposed to risk of both hypothermia and hyperthermia, even at mild cold or
heat exposure. Studies aimed at age related changes in mechanisms of thermoregulation to explain the
increased risk of elderly failed to observe differences in heat loss between young and elderly. This might be caused by a lumped approach of calculation of heat loss through mean skin temperature without
incorporation of temperatures of the extremities.
Study objective
Test the hypothesis that a divisional calculation of heat loss, and incorporation of skin temperature of the extremities during mild cold exposure will indicate an age effect on heat loss between young and elderly. An additional purpose is to test whether age effects on hysteresis are observable between cooling and warming subjects.
Study design
N/A
Intervention
Subjects subjected to a mild cold (airtemperature 20C) and mild heat exposure (airtemperature 35C).
Boris Kingma
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
+31 43 388 4260,
b.kingma@hb.unimaas.nl
Boris Kingma
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
+31 43 388 4260,
b.kingma@hb.unimaas.nl
Inclusion criteria
1. Caucasian healthy male;
2. Age between 18 to 28 years or age between 68 to 78 years;
3. 20 kg/m2 < BMI < 25 kg/m2;
4. 15% < Fat percentage < 20%;
5. 1.8 m2 < Dubois skin area < 2.0 m2;
6. 80mmHg < Mean arterial pressure < 90mmHg (rest, supine position).
Exclusion criteria
1. Female;
2. History of cardiovascular disease;
3. Carrier of electrically-sensitive implanted devices;
4. Deviant core temperature at day of experiment;
5. General feeling of illness at day of experiment.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1892 |
| NTR-old | NTR2007 |
| Other | MEC Maastricht University : 09-3-049 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |