No registrations found.
ID
Source
Brief title
Health condition
Patients with a suspicion of myocardial ischemia /necrosis
Sponsors and support
Hein Hogerzeil Stichting
Intervention
Outcome measures
Primary outcome
•Percentage of patients with or without infarct diagnosis in the different HEART score categories (0-3, 4-6, >6)
Secondary outcome
•Discharge Diagnosis other than myocardial infarction
•Diagnostics used in ER
•Duration of Hospital Stay (hrs, days)
•Costs
Background summary
A prospective observational trial to assess the value of the HEART score in the pre-hospital phase (ambulance) in patients with a clinical suspicion of acute myocardial infarction. The trial is performed in close collaboration with ambulance paramedics. In the area of Zwolle, Deventer and Amersfoort, Ruling-Out low risk patients will be of most interest. In the area of Utrecht, the Rule-In part of the study has started to identify patients at high risk of having acute myocardial infarction. These results will be combined to assess the best cut-off value for triaging patients with a clinical suspicion of cardiac ischemia . A detailed description of the overall FAMOUS TRIAGE project will be ready the beginning of 2014.
Study objective
Risk stratifying patients in the pre-hospital phase(ambulance or GP) by using the validated HEART score
Study design
•Discharge from ER/Hospital
•30 day FUP
Intervention
Pre-hospital venous blood sampling and assessment of the modified HEART score.
Groot Wezenland 20
A.W.J. Hof, van 't
Groot Wezenland 20
Zwolle 8011 JW
The Netherlands
+31 (0)38 4242374
hof@diagram-zwolle.nl
Groot Wezenland 20
A.W.J. Hof, van 't
Groot Wezenland 20
Zwolle 8011 JW
The Netherlands
+31 (0)38 4242374
hof@diagram-zwolle.nl
Inclusion criteria
•All out-of-hospital patients visited by an ambulance and a pre-hospital clinical suspicion of
acute myocardial infarction
•Transfer to a hospital
•Age ≥ 18 years
Exclusion criteria
•Comatose state
•Cognitive impairment
•Pregnancy
•(Cardiogenic) shock
•Cardiac asthma
•Sustained ventricular tachyarrhythmia
•End stage renal disease (dialysis patients)
•No pre-hospital 12-lead ECG performed or available
•ST-segment elevation
•An obvious non-cardiac cause for the chest complaints, e.g. trauma, pneumothorax,
pneumonia, etc.
•Strong Suspicion of aortic dissection or pulmonary embolism
•New onset left branch bundle block (LBBB)
•Confirmed AMI <10 days prior to inclusion
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4039 |
| NTR-old | NTR4205 |
| Other | RAV IJsselvecht : Isala Zwolle |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |