No registrations found.
ID
Source
Brief title
Health condition
Childhood constipation (obstipatie op de kinderleeftijd).
Sponsors and support
Intervention
Outcome measures
Primary outcome
Short circuit current.
Secondary outcome
Base current;
Base potential difference.
Background summary
A trial set up to evaluate the possible difference between chloride secretion healthy controls versus constiapted children.
Study objective
Disturbed chloride secretion in constipated children versus controls.
Study design
As we are not treating patient: we do not have time points.
Intervention
Biopsies from patients will be mounted in ussing chambers to measure the short circuit current and differential potential. We are not treating patients but we are asking them for 2 extra biopsies when they are undergoing coloscopic treatment or undergoing rectal biopsies to exclude Hirschsprung's disease.
Department of paediatric gastroenterology
Postbus 22660
N. Bekkali
Amsterdam 1100 DD
The Netherlands
+31-205662906
Department of paediatric gastroenterology
Postbus 22660
N. Bekkali
Amsterdam 1100 DD
The Netherlands
+31-205662906
Inclusion criteria
Constipation as defined by the the ROME III criteria.
Exclusion criteria
1. Gastrointestinal surgery;
2. Metablic disease;
3. IBD (Crohn's disease, CU);
4. Genetic syndromes (Down's disease);
5. Colonic cancer.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1033 |
| NTR-old | NTR1066 |
| Other | : ClC2 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |