No registrations found.
ID
Source
Brief title
Health condition
Patients with suspected coronary artery disease
Sponsors and support
Intervention
Outcome measures
Primary outcome
MSCT may improve (as compared to MPI) the diagnosis of patients presenting with chest pain complaints and an intermediate likelihood of CAD.
Particularly in these patients, a non-invasive test with a high specificity (to exclude CAD) is needed to allow optimal management of patients. Currently, MPI is used for this purpose, but the specificity of MPI is suboptimal (70%).
Secondary outcome
N/A
Background summary
N/A
Study objective
In patients presenting with chest pain complaints and an intermediate risk of coronary artery disease, Multi-Slice Computed Tomography (MSCT) will have a higher specificity as compared to myocardial perfusion imaging (MPI). Accordingly, MSCT may serve as an accurate first-line evaluation tool.
Study design
N/A
Intervention
MSCT coronary angiography in addition to myocardial perfusion imaging (MPI).
Department of Cardiology,
P.O. Box 9600
J.J. Bax
Albinusdreef 2
Leiden 2300 RC
The Netherlands
+31 (0)71 5262020
j.j.bax@lumc.nl
Department of Cardiology,
P.O. Box 9600
J.J. Bax
Albinusdreef 2
Leiden 2300 RC
The Netherlands
+31 (0)71 5262020
j.j.bax@lumc.nl
Inclusion criteria
Adult patients (having obtained legal majority age) with chest pain complaints and an intermediate pre-test likelihood of CAD (based on the Diamond and Forrester method) with the need for additional imaging studies to evaluate the presence/absence of CAD.
Exclusion criteria
Fertile women, patients with severe renal failure, patients presenting with a known allergy to iodine contrast media, patients included in another clinical trial, patients under guardianship, and patients whose degree of cooperation is incompatible with carrying out the study.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL446 |
| NTR-old | NTR486 |
| Other | : N/A |
| ISRCTN | ISRCTN65675235 |