No registrations found.
ID
Source
Brief title
Health condition
-Asthma (astma)
-Exercise induced bronchoconstriction (inspanningsastma)
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main objective of this study is the measurement of pulmonary function (change in FEV1, FEV0.5 and FEF50) during and post-exercise in young children with asthmatic features. Thus the percent change in pulmonary function (FEV1, FEV0.5 and FEF50) during and post-exercise.
Secondary outcome
1. Analysis of anthropometric measures, clinical features, medication use and history (measured by extensive history) of children with a positive or negative exercise provocation challenge;
2. Analysis of the feasibility of a newly designed exercise provocation challenge using a jumping castle.
Background summary
N/A
Study objective
The aim of this study is to investigate the course of EIB in young asthmatic children, by using a newly designed exercise provocation challenge.
Study design
One visit.
Intervention
No intervention, other than the exercise provocation challenge, will be investigated. An exercise provocation challenge is part of the routine clinical evaluation of patients with exercise induced symptoms or asthma. However, an exercise provocation challenge in the evaluation of asthmatic children aged 5 till 7 years isn’t widely used and can therefore be seen as an intervention. Moreover, our newly designed exercise provocation challenge, using a jumping castle is experimental.
Thus the intervention used in our study is a newly designed exercise provocation challenge.
This exercise provocation challenge exists of jumping on a jumping castle for at least 4 minutes (target is a 6 minute lasting exercise at 80% of the predicted maximum heart rate). Before, during and after exercise, patients perform pulmonary function measurements (flow volume curves).
Haaksbergerstraat 55
J.C. Leeuwen, van
Enschede 7513 ER
The Netherlands
+31 (0)53 4872310
vanleeuwen.janneke@gmail.com
Haaksbergerstraat 55
J.C. Leeuwen, van
Enschede 7513 ER
The Netherlands
+31 (0)53 4872310
vanleeuwen.janneke@gmail.com
Inclusion criteria
1. Clinical history of asthma symptoms;
2. Age 5 till 7 years;
3. Ability to perform reproducible lung function tests;
4. Clinically stable period at least 4 weeks before the study period (no hospital admission or use of systemic corticosteroids).
Exclusion criteria
1. Use of systemic corticosteroids in the last 4 weeks prior to the study;
2. Use of long acting bronchodilators 24 hours before testing;
3. Use of short acting bronchodilators 8 hours before testing;
4. Use of leukotriene antagonists 24 hours before testing;
5. Other pulmonary or cardiac disorder.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL2892 |
| NTR-old | NTR3038 |
| Other | METC : P11-29 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |