No registrations found.
ID
Source
Brief title
Health condition
disorder primary hemostasis
Sponsors and support
Intervention
Outcome measures
Primary outcome
Peri- and postoperative blood loss.
Secondary outcome
1. Pre- and postoperative hemoglobin;
2. Number of perioperative blood transfusion;
3. Perioperative fluid infusion;
4. Postoperative drainage.
Background summary
N/A
Study objective
N/A
Study design
N/A
Intervention
Preoperative infusion placebo / desmopressin (< 50 kg: 15 mcg, 50-100kg: 30 mcg, > 100 kg: 45 mcg).
S.C. Marczinski
Willy Brandtlaan 10
Ede 6716 RP
The Netherlands
+31 (0)318 435546
Marczinskis@zgv.nl
S.C. Marczinski
Willy Brandtlaan 10
Ede 6716 RP
The Netherlands
+31 (0)318 435546
Marczinskis@zgv.nl
Inclusion criteria
1. Patients aged over 18 who receive a serotonergic antidepressant (fluvoxamine, fluoxetine, paroxetine, sertraline, venlafaxine, clomipramine, citalopram) at least started two weeks before the surgery;
2. Surgery: orthopedic, abdominal, breast.
Exclusion criteria
1. No informed consent;
2. Disorder in primary hemostasis;
3. Hyponatremia (sodium (serum) < 130 mmol/l);
4. Laparoscopic surgery;
5. Use of vitamin K antagonists, aspirin, iron supplements, methotrexate, heparin;
6. Acute coronary syndrome (unstable angina and myocardial infarction);
7. Spinal anesthesia during surgery.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL140 |
| NTR-old | NTR175 |
| Other | UMCU : 04-298 |
| ISRCTN | ISRCTN10353850 |