No registrations found.
ID
Source
Health condition
Children aged 1-4 years with recurrent upper respiratory tract infections
Sponsors and support
Medical Spectrum Twente
Intervention
Outcome measures
Primary outcome
Average number of days a month with a pediatrician diagnosed upper respiratory tract infection
Secondary outcome
- Immunological changes in bloodtests
- Parents' absence of work
- Use of antibiotics
- Cholesterol values
Background summary
Background: Immunological mechanism and dietary nutrients are important mediators in the health of children. In this intervention study a dietary advice is given to children between 1 and 6 years of age with recurrent respiratory tract infections. Could a change in nutrient intake result in an altered clinical outcome? Design: In this prospective cohort study 61 children were included and evaluated at a paediatric outpatient clinic. The control group consisted of 32 children included at an infant welfare centre. The patient group followed the dietary advice (green vegetables, beef, whole milk, full-fat butter) for three months, in which parents filled out their dietary intake and health status on a daily basis. A follow up form was filled out by the parents 3 months after completion of the study period. For statistical analysis the programme SPSS version 15.0 was used. Results: In the patient group there was a statistical significant reduction in days with a respiratory infection (15.7 to 11.5 days a month), subfebrile temperature days (1.9 to 0.5 days a month) and febrile temperature days (1.0 to 0.7 days a month) compared to the control group. Also, antibiotic use decreased significantly. No significant changes were measured in body mass index. Conclusions: A change of diet towards green vegetables, beef, whole milk and full-fat butter has positive health effects in children. This diet may work by adding nutrients to optimize immunological mechanisms. There were no adverse effects and it can be utilized by general pediatricians and general practitioners.
Study objective
A nutrient rich diet can improve immunological functions and reduce respiratory infections
Study design
t= 0, 3 and 6 months
Intervention
A nutrient rich diet consisting of beef, green vegetables, whole milk and butter, in age appropriate portions
Inclusion criteria
- age 1-4 years
- recurrent upper respiratory tract infections
- understanding of Dutch language by parents
Exclusion criteria
- immunological deficiencies
- cow's milk allergy
- disorder of intestinal absorption
- prophylactic use of antibiotics
- disorders requiring a special diet
- relevant congenital or anatomical abnormalities
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4693 |
| NTR-old | NTR4898 |
| Other | METC Enschede : P14-39 |
Summary results
http://file.scirp.org/Html/11-2700861_37865.htm