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ID
Source
Brief title
Health condition
Long-term consequences of burns
Sponsors and support
Association of Dutch Burn Centres (ADBC)
P.O. Box 1015
1940 EA Beverwijk
Grant number: 15.102
Intervention
Outcome measures
Primary outcome
Long-term generic HRQL of children and adult burn survivors will be assessed by the ‘EuroQol-5D-5L + cognitive domain’ (EQ-5D-5L).
Secondary outcome
The secondary outcome parameters of this study are long-term burn specific HRQL, long-term functions, activities and participation of burn survivors:
Burn specific HRQL
o Score on the Burns Specific Health Scale-brief (BSHS-B) in adults
o Score on the Burn Outcome Questionnaire (BOQ) in children aged 5 – 18 years
Scar quality
o Score on the Patient and Observer Scar Assessment Scale (POSAS) patient score
Itching of scar
o Score on the POSAS patient score
Depressive symptoms
o Score on the Beck Depression Inventory (BDI-II-NL)
Perceived stigmatization
o Score on the Perceived Stigmatization Questionnaire (PSQ) in adults
Participation
o Score on the Work Productivity and Activity Impairment General Health (WPAI-GH)
Additional parameters, only for the cohort on extensive burns:
Scar quality
o Score on the POSAS observer score
Contractures
o Reconstructive surgery
Muscular strength
o Grip strength (Force in Newton) measured by a Hand-Held Dynamometer
Aerobic capacity
o Maximum achieved wattage during the Steep Ramp Test (SRT)
Habitual physical activity patterns
o Score on the Habitual Physical Activity Questionnaire (PAQ)
Fatigue
o Score on the Brief Fatigue Inventory (BFI)
Body composition
o Body mass index (BMI) and waist circumference
Background summary
SUMMARY
Rationale: Burden of disease calculations are an important resource in public health. The burden of disease aggregates all health consequences of a disease in one metric and is increasingly used for priority setting in health care, surveillance and interventions. For the calculation of the burden of disease, information on long-term consequences of the specific disease is needed. Currently, little is known about the long-term consequences and secondary conditions after burns. Therefore, calculation of the burden of burns is challenging.
Objective: To obtain a comprehensive overview of long-term (≥5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
Study design: A multicentre cross-sectional study.
Study population: All burn patients (children and adults) who have been admitted to one of the three Dutch burn centres in the period August 2011 – July 2013 and with a hospital stay of more than one day or who have had surgical treatment for their burns.
For the cohort on extensive burns: all patients with extensive burns (over 20% total body surface area (TBSA)) in adults, over 10% TBSA in children <10 years or adults >50 years or TBSA third degree > 5% who had an admission to one of the three Dutch burn centres in the period 2010 – 2013.
Intervention (if applicable): Not applicable
Main study parameters/endpoints: To assess long-term health-related quality of life and long-term functioning, activities and participation of burn survivors, questionnaires that include questions on health-related quality of life, on body functioning, on participation and on environmental factors will be assessed in all patients.
In addition, to fully elucidate long-term consequences of extensive burns, muscular strength, aerobic capacity, contractures, body composition, fatigue, and habitual physical activity will be assessed in patients with extensive burns.
Study objective
An observational study to obtain a comprehensive overview of long-term (≥5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
Study design
Outcomes will assessed once. At least 5 years after burns.
Intervention
None
Inclusion criteria
- Patients of all ages with a hospital stay of ≥1 night or with surgical treatment for their burns in the period August 2011 – July 2012
- Informed consent
For the extended cohort on severe burns:
- Patients (≥10 - ≤50 years old) with major burns (over 20% TBSA)
- Patients (<10 and >50 years old) with major burns (over 10% TBSA)
- Patients with TBSA third degree > 5%
Exclusion criteria
Insufficient knowledge of the Dutch language
Deceased
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL6249 |
| NTR-old | NTR6407 |
| CCMO | NL59981.101.16 |
| OMON | NL-OMON43284 |