No registrations found.
ID
Source
Brief title
Health condition
Migraine
Sponsors and support
Intervention
Outcome measures
Primary outcome
Depends on sub-study protocol
Secondary outcome
Depends on sub-study protocol
Background summary
Biochemic profiling in migraine: a lare study into clinical, neuroimaging and biochemical (a.o. serum and cerebrospinal fluid) profiling of migraine patients during different phases of the migraine attack, in comparison with non-headache individuals. The overall study includes up to 500 participants, distributed over varioud substudies. Both spontaneous and nitroglycerin-triggered migraine attacks are studied. The study is mainly observational; the intervention in some sub-studies is nitroglycerin-triggering, which is an international well-esthablished model to facilitate the studying of migraine attacks
Study objective
In migraine, a biomarker (either via neuroimaging or biochemical profiling) can be found to distinguish patient from non-patients and to understand how migraine attacks initiate and develop
Study design
Start 2008; in accordance to local METC multiple extensions
Intervention
In most sub-study protocols: none; in some: nitroglycerin triggering
Inclusion criteria
Migraine headaches; over 18 years of age
Exclusion criteria
Other primary headaches; other neurologis conditions or medication that interfere with specific sub-study goals
Design
Recruitment
IPD sharing statement
Plan description
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8203 |
| Other | METC LUMC : METC P07.079 |