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ID
Source
Brief title
Health condition
Osteoporosis / low bone mineral density
Sponsors and support
Intervention
Outcome measures
Primary outcome
Lumbar spine BMD
Secondary outcome
Blood markers of bone metabolism (P1NP, CTX).
Background summary
Bone health is a critical factor for athletes as bones provide the levers for muscles to move the joints, and strong bones decrease the risk of bone fractures. Particularly cyclist can benefit from exercise and nutrition interventions to stimulate bone health, as this population is characterized by an impaired bone mineral density (BMD). Jumping exercise has been identified as a feasible and effective exercise intervention to increase BMD. Furthermore, preliminary evidence suggests that collagen supplementation may also stimulate bone collagen synthesis. It is currently unknown whether combined collagen supplementation and jump training can increase BDM in elite cyclists. The main objective of the current project is to assess the effect of long-term jump training combined with collagen supplementation on BMD in elite cyclists.
Study objective
Long-term (18 weeks) jump training combined with collagen supplementation will increase BMD in elite cyclists.
Study design
PRE (week -1), POST (week 19)
Intervention
Jump training and collagen supplementation
Inclusion criteria
• Elite cyclists status
• Age ≥16 and ≤35 years.
• Willing to give blood samples
• Willing to comply with study procedures
Exclusion criteria
• Blood donation during the study period
• Severe allergy to nuts or intolerance to gluten, as supplements are being produced in factory that may have used nuts or gluten previously
• Use of antibiotics in the past month
• Medical condition that can interfere with the study outcome (i.e. cardiovascular disease, pulmonary disease, rheumatoid arthritis, orthopaedic disorders, renal disease, liver disease, diabetes mellitus, inflammatory disease, cognitive impairment, and thyroid or parathyroid disease)
• Use of medications known to interfere with selected outcome measures (i.e. systemic corticosteroids)
• (Chronic) injuries of the locomotor system that can interfere with the intervention.
• Current participation in another biomedical research study.
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
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Other (possibly less up-to-date) registrations in this register
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In other registers
| Register | ID |
|---|---|
| NTR-new | NL9770 |
| Other | METC Zuyderland : METCZ20210113 |