No registrations found.
ID
Source
Health condition
cardiac conduction disorder, heart rhythm disorders, hartritmestoornis, hartritmestoornissen, cardiac rhythm disorder
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study endpoint is further development and validation of mathematical methods and recording techniques, to reconstruct epicardial potentials from body-surface potentials (BSPs) and a torso-heart geometry. This development and validation can only be performed when BSP and torso-heart geometrical data are available.
Secondary outcome
The secondary study endpoints include disease-specific abnormalities in epicardial reconstructions or in body-surface potential maps.
Background summary
Non-invasive reconstruction of electrical heart activity can yield important scientific and clinical insights in cardiac rhythm disorders. In this study, we aim at developing methods for reconstructing electrical heart activity non-invasively, and to use these methods to investigate cardiac rhythm disorders to answer clinical and scientific questions.
Study objective
N/A
Study design
Recording of body-surface potentials and (if applicable) a CT scan at timepoint 1. Follow-up might follow at a later timepoint, at which body-surface potentials will be re-recorded.
Intervention
The subjects will be asked to undergo a procedure in which 256 recordings of body-surface potentials (ECGs) are made. For this purpose, strips of electrodes will be attached to the subject's torso.
When the patient (for diagnostic reasons unrelated to this research) will receive a cardiac CT scan, this will be extended to also image the body-surface electrodes.
Paul Volders
Maastricht 6202 AZ
The Netherlands
+31 (0)43 3875099
p.volders@maastrichtuniversity.nl
Paul Volders
Maastricht 6202 AZ
The Netherlands
+31 (0)43 3875099
p.volders@maastrichtuniversity.nl
Inclusion criteria
Age ≥ 18 years and one or more of the following:
1. Conditions that might alter electrical conduction properties in the heart, including (but not limited to): Brugada syndrome (BS), Arrhythmogenic right ventricular cardiomyopathy (ARVC);
2. Implanted cardiac device, such as pacemaker or implantable cardioverter defibrillator;
3. The sole need for cardiac CT as technique to exclude cardiac disease (reference group).
Exclusion criteria
Known strong reaction against electrode attachment.
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL2871 |
| NTR-old | NTR3016 |
| CCMO | NL32128.068.11 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON53169 |