No registrations found.
ID
Source
Health condition
neuromuscular monitoring, TOF-Cuff, TOF-Watch
Sponsors and support
Intervention
Outcome measures
Primary outcome
the bias and limits of agreement of the TOF-Cuff NMT Monitor and the TOF-Watch SX acceleromyograph for perioperative neuromuscular monitoring
Secondary outcome
the bias and limits of agreement of the TOF-Cuff NMT Monitor and the TOF-Watch SX acceleromyograph for perioperative neuromuscular monitoring?
Study objective
The TOF Cuff NMT monitor is as reliable as the TOF-Watch SX acceleromyograph for perioperative neuromuscular monitoring.
Study design
Time to onset of neuromuscular block is measured for both devices. Onset is defined as time from start of injection until 95% depression of T1. After this paired measurements are taken in all phases of neuromuscular block : the profound/deep phase, in the moderate phase and in the recovery phase. When, during the recovery/progression of the neuromuscular block, the TOF-watch shows a measurement in the range of the next study-measurement the corresponding TOF-cuff value is noted (see table 1.). Because both devices will measure every 30 seconds the maximal time between two measurements of both devices is 15 seconds. In each predefined range of neuromuscular relaxation 3 measurements will be taken to correct for slight variations of the measurements in each device.
Intervention
Perioperative neuromuscular monitoring with both the TOF-Cuff NMT Monitor and the TOF-Watch SX acceleromyograph.
Inclusion criteria
15 patients, age >18 years, American Society of Anesthesiologists physical status I-III, undergoing elective surgery in supine position with both arms abducted, under general anesthesia with orotracheal intubation aided by administration of a non-depolarizing neuromuscular blocking agent.
Exclusion criteria
- No informed consent
- Neuromuscular disease.
- Diabetes Mellitus
- Indication for rapid sequence induction
- Expected difficult intubation or ventilation
- Pregnancy
- Allergy to neuromuscular blocking agent (rocuronium)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL6735 |
| NTR-old | NTR6913 |
| Other | CMO-code : 2017-3858 |