No registrations found.
ID
Source
Brief title
Health condition
Insomnia, phenotypes
Sponsors and support
Intervention
Outcome measures
Primary outcome
The change from baseline to post-treatment on a composite score that summarizes subjectie insomnia complaints, queried daily through an internet diary.
Secondary outcome
Actigrapphically estimated objective sleep parameters.
Background summary
Insomnia is a condition that affects about 10% of the Western population. At present, the most common solution provided by primary care givers is pharmacological treatment. However, pharmacological treatments have a high prevalence of negative side effects. Two more recently developed treatments are chronobiological treatment (CT) and cognitive behavioral therapy (CBT). They appear safer and have more sustained effects. A problem facing implementation of CBT-I is that there are hardly any skilled therapists. Web-based CBT-I may this alleviate this problem.
A second opportunity for optimization of treatment is based on the contention that the people with insomnia most likely represent a heterogeneous mix of different subtypes, with different underlying causes and expected treatment response. This is the first step in the development of a protocol for individualized optimal treatment for specific phenotypes of insomnia, where each phenotype may show different CT and CBT-I demands.
In a systematic way the effectiveness of CT, CBT-I and their combination will be evaluated for the different phenotypes.
Study objective
Insomnia patients form a heterogeneous group, each phenotypes of insomnia will show different therapeutic demands.
Study design
Baseline, 5 weeks and 10 weeks.
Intervention
Web-based cognitive behavioral therapy for insomnia (CBT-I)
3 forms of chronobiological therapy (CT):
-Bright light therapy
-Thermoregulatory therapy
-Physical activity
Combinations of CBT-I and CTs.
Meibergdreef 47
Kim Dekker
Amsterdam 1105 BA
The Netherlands
020-5665492
k.dekker@nin.knaw.nl
Meibergdreef 47
Kim Dekker
Amsterdam 1105 BA
The Netherlands
020-5665492
k.dekker@nin.knaw.nl
Inclusion criteria
1) 18-70 years of age;
2) Insomnia.
Exclusion criteria
1) Other neurological or psychiatric disorders
eye diseases;
2) Cardiovascular or movement disorders;
3) Shiftworkers;
4) Use of sleep medication 3 months prior to inclusion;
5) Habitual level of light intake, physical activity or bathing habits equal to therapy.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL3828 |
| NTR-old | NTR4010 |
| Other | METc VUmc : 12/472 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |