No registrations found.
ID
Source
Brief title
Health condition
Vicryl Plus
coated sutures
Triclosan
wound healing/ wondgenezing
Sponsors and support
Intervention
Outcome measures
Primary outcome
Wound healing: wound dehiscence and complications are registrated.
Secondary outcome
Scar quality:
Colorimetric measurement 1 month after surgery Measurements are performed under standard conditions at 4 fixed test sites.
Subjective scar assessement by patients and one primary observer using the POSAS scale.
Background summary
Wound infection is a major contributor to postoperative morbidity. One
potential cause or co-factor is the use of suture material. A recently
introduced subcutaneous suture is coated with triclosan (TC), an antiseptic
drug. It is suggested to reduce wound complications and improve scar
quality.
Methods:
To investigate the effect of TC on wound healing a double blind prospective
study in women undergoing a breast reduction was performed. Each patient was
her own control. After randomization the TC coated sutures were used either
on the left or right side. The contra lateral side was used as the control.
The incidence of dehiscence, postoperative redness and subjective parameters
of scar quality were studied.
Study objective
Triclosan coated sutures might have an positive effect on wound healing and thus can improve scar quality.
Study design
N/A
Intervention
Standard suture on control site;
triclosan coated suture on study site.
Inclusion criteria
1. Women between 16 and 65 years of age with bilateral breast size higher than cup DD;
2. Clinical complaints such as intertrigo, head neck and/or shoulder complaints;
3. Undergoing a breast reduction.
Exclusion criteria
1. Patients with:
a. diabetes;
b. skin diseases;
c. history of keloid formation;
d. use of corticosteroids and other immunosuppressive medication;
e. metabolic and/or degenerative diseases.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL957 |
| NTR-old | NTR983 |
| Other | : N/A |
| ISRCTN | ISRCTN32724539 |