No registrations found.
ID
Source
Health condition
autism, cognitive behavioral therapy, mindfulness based stress reduction
Sponsors and support
Intervention
Outcome measures
Primary outcome
reduction on anxiety scale and the depression scale of the hospital anxiety and depression scale (HADS)
Secondary outcome
1. changes on the social responsivity scale
2. changes in positive and negative affect on the global mood scalee
Background summary
A three-arm RCT among 180 adults with ASD (60 MBSR, 60 CBT, and 60 treatment as usual, (TAU)), conducted in an outpatient setting with measurements at the start and end of the 13 week treatment period, and at 3 months follow-up. Instruments include the hospital anxiety and depressions scale, rumination, irrational belief and mindfulness scales, and an autism symptom checklist
Study objective
Despite high rates of anxiety and depression among adults with ASD, treatment methods for these comorbid conditions have not been systematically studies or compared in this patient population. Recently, MBSR and CBT protocols were adapted for adults with ASD and could be excellent candidate therapies for reducing anxiety and depression.
The study looks at the ability of both treatment methods to reduce anxiety and depression symptoms among adults with ASD, and to determine which therapy is best suited for which patient.
Study design
in each cycle:
Mo: at intake
M1: at start of the 13 week treatment period
M1a: after 4 weeks treatment
M1b: after 8 weeks treatment
M2: on completion of 13 week treatment period
M3: at 3 months follow up
Intervention
1. cognitive behavioral therapy addopted for adults with ASD (Schuurman, 2012) over a 13 week period
2. Mindfullness based stress reduction therapy for adults with ASD (Spek, 2012) over a 13 week period
3. Treatment as ususal
PO box 5003
B. Sizoo
Deventer 7416 SB
The Netherlands
+31 575 639 652
b.sizoo@dimence.nl
PO box 5003
B. Sizoo
Deventer 7416 SB
The Netherlands
+31 575 639 652
b.sizoo@dimence.nl
Inclusion criteria
1. adults with a clinical diagnosis of ADHD
2. normally intelligent
3. able to do homework assignments associated with treatment
4. score of > 8 on hospital anxiety and depression scale (HADS)
Exclusion criteria
- former treatment with mindfulness or cognitive behavioral therapy for adults with autism
- too sensitive for group treatment
- psychosis or under influence of alcohol or drugs
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4082 |
| NTR-old | NTR4233 |
| CCMO | NL40743.072.12 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON36888 |