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ID
Source
Health condition
arm support
shoulder function
neuromuscular disease
arm ondersteuning
schouderfunctie
neuromusculaire aandoeningen
FSHD
Sponsors and support
Focal Meditech BV
Intervention
Outcome measures
Primary outcome
The primary outcome measures are shoulder loads and muscular effort
Secondary outcome
The secundary outcome measure is shoulder load calculated from intertial magnetic measurements
Background summary
Summary
For people with Facioscapulohumeral dystrophy (FSHD), an assistive device in the form of an arm
support can effectively increase the range of motion by compensating for the arm weight, thus
ultimately resulting in an increased functionality. However, the exact implications of arm support
systems on shoulder load, shoulder instability and muscle weakness have not been properly
investigated so far. Shoulder loads estimated with musculoskeletal simulations, shoulder stability and
associated muscular effort of up to 15 subjects with FSHD and up to 15 healthy controls will be
compared during the performance of standardized upper extremity tasks with and without an arm
support system. In preparation of transferring to home measurements, movements will be recorded
with a portable inertial magnetic measurement system in addition to traditional, laboratory bound
motion capture equipment and EMG. The feasibility and validity of shoulder loads estimated with
musculoskeletal simulations based on inertial magnetic data will be established.
Question1: How are muscular efforts of persons with FSHD and healthy controls related to shoulder
loads and stability while per forming standardized upper extremity tasks with and without an arm
support?
Hypothesis1: Activity changes in the muscles involved in scapular stability depend on the magnitude
and direction of the shoulder load generated by the arm support. The activity onset of the muscles
involved in scapular mobility will be affected by the arm support, while coordination strategies of
these muscles will remain unaltered.
Question2: What is the feasibility and validity of musculoskeletal simulated shoulder load predictions
based on inertial magnetic data.
Hypothesis2: Biomechanical outcome parameters from musculoskeletal simulations based on inertial
magnetic data are expected to be similar to simulations based on Optotraks’ position data.
Study objective
NA
Study design
One session, in which kinematics, muscular effort (% EMG) and inertial magnetic data will be collected.
Intervention
Cross-sectional study in which two groups will be compared; a healthy group of adults acting as control group and a group of adults with FSHD. Both groups will be asked to complete the same movement protocol with and without arm support.
Alessio Murgia
Antonius Deusinglaan 1
Groningen 9713 AV
The Netherlands
+31 50 361 6036
a.murgia@umcg.nl
Alessio Murgia
Antonius Deusinglaan 1
Groningen 9713 AV
The Netherlands
+31 50 361 6036
a.murgia@umcg.nl
Inclusion criteria
- Healthy adults:
o Men and women, aged between 18-75 years
o Able to read/understand Dutch
o Able to give written informed consent
- Adults with FSHD:
o Men and women, aged between 18-75 years
o Able to read/understand Dutch
o Able to give written informed consent
o Able to transfer from wheelchair to chair with side- and lower back-rest
o Brooke scale 3 or 4 (3 of both)
Exclusion criteria
- Healthy adults:
o Diagnosed pathologies that could interfere with the measurement results.
o Presence of pain in the shoulder.
o History of severe trauma of the shoulder within the previous two years (e.g. fracture, luxation).
o Prior experience in using the Gowing arm support.
- Adults with FSHD:
o Comorbidities that could interfere with the measurement results.
o Incapable of abducting or elevating (anteflexion) the affected arm > 30 degrees.
o Previous surgery of the affected shoulder.
o Extrinsic causes of shoulder pain.
o History of severe trauma of the shoulder within the previous two years (e.g. fracture, luxation).
o Prior experience in using the Gowing arm support
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5564 |
| NTR-old | NTR5685 |
| CCMO | NL55711.042.15 |
| OMON | NL-OMON46136 |