No registrations found.
ID
Source
Brief title
Health condition
Esophageal cancer, Barrett’s esophagus, HD endoscopy, computer-aided diagnosis
Sponsors and support
Intervention
Outcome measures
Primary outcome
- Classification scores of the CAD system
Secondary outcome
- Speed of the algorithm
Background summary
Esophageal cancer is one of the most lethal tumors worldwide. When esophageal cancer is diagnosed, it is often in a late stage and only half of the patients undergo curative surgical removal of the esophagus. When discovered in an early stage, it can be treated minimally invasive without removing the esophagus with excellent outcome. Patients with Barrett’s
esophagus (BE) have an increased risk of esophageal adenocarcinoma (EAC). Therefore, they undergo regular
endoscopy for early cancer detection.
EAC in a Barrett’s esophagus is difficult to detect during surveillance endoscopies. This is partly because of its subtle appearance and partly because most endoscopists rarely encounter early BE neoplasia and therefore are unfamiliar with its endoscopic appearance . A computer aided detection (CAD) system might assist endoscopists in the recognition and subsequent characterization of early BE neoplasia, thereby improving efficacy of BE surveillance. The aim of this study is to develop a CAD algorithm using high quality endoscopic imagery of BE neoplasia.
Study objective
The development of a computer aided detection (CAD) system might be able to assist endoscopists in the recognition and subsequent characterization of early Barrett's neoplasia, thereby improving efficacy of BE surveillance.
Study design
not applicable
Intervention
No interventions will take place.
For this study, extra endoscopic imagery will be obtained by making endoscopic images and (zoom) videos.
Inclusion criteria
Patients >18 years with:
- non-dysplastic Barrett's esophagus; or
- dysplastic Barrett's esophagus; or
- early adenocarcinoma of the esophagus
Exclusion criteria
- Patients previously treated for Barrett neoplasia
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL6835 |
| NTR-old | NTR7072 |
| Other | METC AMC : W17_251 |