No registrations found.
ID
Source
Brief title
Health condition
cardiovascular disease; preeclampsia; endothelial dysfunction; diastolic dysfunction; women's health
cardiovasculaire aandoeningen; preeclampsie; endotheeldysfunctie; diastolische dysfunctie; gezondheid voor vrouwen
Sponsors and support
Intervention
Outcome measures
Primary outcome
cardiovascular risk factors and diastolic funtion
Secondary outcome
metabolic syndrome, diabetes
Study objective
We hypothezise that both hypertension in pregnancy and cardiovascular disease in later life share pathophysiological features of endothelial dysfunction.
Study design
9-16 years postpartum; 1 visit
Intervention
questionnaire, antroprometrics, venous blood samples, cardiac ultrasonography.
Inclusion criteria
Women with a history of early preeclampsia (<34 weeks gestation) who gave labour in the a UMC between 1998-2005 (cases)
Women with a history of uncomplicated pregnancy who gave labour after 37 weeks of gestation in a UMC between 1998-2005 and matched for age and delivery date (controls)
Exclusion criteria
Multiple pregnancy, chronic hypertension, diabetes mellitus before pregnancy or gestational diabetes during the index pregnancy, cardiovascular disease before pregnancy, renal disease, coagulation disorders, pregnancy complicated by fetal anomalies. For controls exclusion: no pregnancies complicated by vascular complications.
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5157 |
| NTR-old | NTR5297 |
| CCMO | NL38972.029.12 |
| OMON | NL-OMON45089 |