No registrations found.
ID
Source
Brief title
Health condition
Rhegmatogenous retinal detachment is an ocular condition in which the neuroretina has detached from the underlying retinal pigment epithelium. This may result in lasting problems with visual function, even if the retina becomes reattached through surgery. Problems may include reduced visual acuity, metamorphopsia, and reduced contrast acuity. These problems occur more frequently when the centre of the retina, the macula, is involved in the detachment.
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. Visual acuity in relation to duration and height of macular detachment;
2. Individual parameters relating to visual function, subjective contentness and morphology of the macula in relation to each other.
Primary study group:
Pre-operative and postoperative at 1, 3, 6 and 12 months.
Secundary study group:
Pre-operative and 1 year after the latest vitreoretinal surgery.
Secondary outcome
1. Correlation between height macular detachment measured by ultrasonography and by optical coherence tomography.
2. Relationship between subjective contentness in the primary and secondary study groups.
Background summary
A rhegmatogenous retinal detachment is a condition that can severly affect visual function, in particular when the macula is involved in the detachment. Previous studies evaluated whether duration of macular detachment or height of macular detachment influenced postoperative visual prognosis. Both factors - taken separately - are of importance, however when looking at duration of macular detachment no significant differences in visual recovery were observed between eyes with macular detachment of 1 to 9 days. The present study will evaluate whether differences in visual recovery can be related more strictly to duration of macular detachment when the data are corrected for height of macular detachment. This may result in a recommendation to change current practice with regard to patient scheduling in vitreoretinal surgery for rhegmatogenous retinal detachment.
Study objective
Optimum timing of surgery for macula off rhegmatogenous retinal detachment can be determined in more detail by taking both duration and height of macular detachment into account.
Intervention
Vitreoretinal surgery according to current practice guidelines.
Department of Ophthalmology,
P.O. Box 30.001
D. Croonen
Groningen
The Netherlands
+31 (0)50 3612510
d.croonen@ohk.umcg.nl
Department of Ophthalmology,
P.O. Box 30.001
D. Croonen
Groningen
The Netherlands
+31 (0)50 3612510
d.croonen@ohk.umcg.nl
Inclusion criteria
Primary study group:
1. Rhegmatogenous retinal detachment with macula off during 1 day to 6 weeks;
2. Retinal reattachment after one surgical intervention;
3. No redetachment during the study period (1 year).
Secondary study group:
same as primary study group, but more than one vitreoretinal surgical procedure is needed to obtain retinal attachment.
Exclusion criteria
1. Pre-existent ocular pathology in the study or fellow eye that significantly influences visual acuity;
2. History of retinal detachment in the study or fellow eye.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL826 |
| NTR-old | NTR839 |
| Other | : N/A |
| ISRCTN | ISRCTN76474643 |