No registrations found.
ID
Source
Brief title
Health condition
SARS-CoV2 infection
Sponsors and support
Intervention
Outcome measures
Primary outcome
Patients will receive regular care as indicated by the treating physician. LUS is performed immediately in the Emergency Department or after admissionto the hospital. SARS-CoV-2 PCR testing will be performed along with standard laboratory testing and other microbiological tests to detect pathogens that cause respiratory tract infection.CT-scan during admission is only performed if this is clinically indicated or protocol during COVID outbreak.
Secondary outcome
•CT report by radiologist(CORADSscore)•
Laboratory results including flocked swab and COVID-19 PCR.•
Laboratory investigations: as determined by the local department, but at least: oCRP, d-dimer, troponin, ferritin, LDH, lymphopenia, NT-proBNP•
LUS results data for 12locations with scoring systemof LUS•Final diagnosis at discharge •
Clinical outcome:discharge, death, IC admission•
Hospitalization days and ICU admission days, number of days on mechanical ventilation
Background summary
Infections with the SARS-CoV2 virus often leads to a pneumonia; this pneumonia is visible with Lung UltraSound (LUS). In daily patient care it is hard to measure the severity of the pneumonia; CRP and other biomarkers are traditionally used for determining the prognosis of patients and lead therapeutic decisions. In this study we investigate whether daily LUS can help in prognostication of the clinical course of the patient and support clinical decisions. Furthermore, we will compare our results with traditional biomarkers. patients will undergo a daily LUS. The progression of pneumonia will be determined with the Lung Aeration Score.
Study objective
The objective of this study is delineating the role of pulmonary ultrasound in determining the clinical course in COVID-19 patients
Study design
every month
Intervention
Lung Ultrasound
Inclusion criteria
Age (≥18 years)
Proven(PCR) or suspected (based on clinical signs and imaging) COVID-19 infection-
Referral or admission for internal, emergency or respiratory medicine-
Certified sonographerpresent
Exclusion criteria
-Pre-existing pulmonary disease or heart failure
-Absence of COVID infection
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8498 |
| Other | METC Radboudumc : 2020-6371 |