No registrations found.
ID
Source
Brief title
Health condition
Colorectal pathology, laxatives, colorectal surgery, postoperative ileus
Sponsors and support
Intervention
Outcome measures
Primary outcome
Time to gastrointestinal recovery, defined as time to first flatus or first defecation.
Secondary outcome
Appreciation of the laxatives being used, overall hospital stay and incidence of postoperative complications (anastomotic leakage, wound infection, intra-abdominal abscess).
Background summary
Postoperative ileus is a well-known consequence of abdominal surgery which leads to prolonged hospital stay.
The objective of this trial is to compare time to gastrointestinal recovery after elective colorectal surgery between patients treated with a laxative versus patients treated with a placebo.
Study objective
Postoperative ileus is a well-known consequence of abdominal surgery which leads to prolonged hospital stay. Over the past years, the implementation of ERAS programs have lead to a reduction in postoperative hospital stay. The use of laxatives after colorectal surgery within these protocols is not yet evidence based.
The objective of this trial is to compare time to gastrointestinal recovery after elective colorectal surgery between patients treated with a laxative versus patients treated with a placebo.
Study design
N/A
Intervention
The laxatives being used in this trial are magnesiumoxide and bisacodyl. Patients will receive the laxative or the placebo for three days postoperatively, twice daily starting on the evening of surgery.
R.L.G.M. Blom
Atrium MC Heerlen afdeling chirurgie, Henri Dunantstraat 5
Heerlen 6401 CX
The Netherlands
+31 (0)45-5766666
r.blom@student.maastrichtuniversity.nl
R.L.G.M. Blom
Atrium MC Heerlen afdeling chirurgie, Henri Dunantstraat 5
Heerlen 6401 CX
The Netherlands
+31 (0)45-5766666
r.blom@student.maastrichtuniversity.nl
Inclusion criteria
Patients planned for elective colorectal surgery will be included regardless of age, underlying pathology or co-morbidity. Procedures to be performed include right hemicolectomy, transversectomy, left-hemicolectomy, sigmoid resection, low anterior resection, polypectomy, abdominoperineal resection, and laparoscopic right or left hemicolectomy.
Exclusion criteria
1. Age <18 years;
2. Emergency procedures;
3. Contra-indications for the laxatives being used;
4. Lacking informed consent.
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1773 |
| NTR-old | NTR1883 |
| CCMO | NL28256.096.09 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON33165 |