No registrations found.
ID
Source
Brief title
Health condition
Esophageal cancer
Sponsors and support
Hanzeplein 1
9700 RB Groningen
The Netherlands
Hanzeplein 1
9700 RB Groningen
The Netherlands
Intervention
Outcome measures
Primary outcome
Application of the near-infrared fluorescence camera safely without disturbing the normal operative procedure.
Secondary outcome
Detection of lymph nodes with the near-infrared fluorescence camera.
Background summary
The primary aim of the study is to assess whether our Near-Infrared
Fluorescence camera may safely be used during esophageal resections. The
secondary aim is the intraoperative detection of lymph nodes using
indocyanine green and a Near-Infrared Fluorescence camera.
Patients undergoing esophagectomy for cancer of the esophagus will
receive an intraoperative peritumoral injection with ICG. Imaging will
subsequently take place using the NIRF camera to assess whether lymph
nodes may be detected.
Study objective
A near-infrared fluorescence camera and a peritumoral injection of indocyanine green may be used for detection of lymph nodes during esophageal resections without affecting the normal operative procedure.
Study design
N/A
Intervention
Peritumoral injection with indocyanine green and subsequent imaging using the intraoperative near-infrared fluorescence camera.
Department of Surgery / BioOptical Imaging Center Groningen <br>
G.M. Dam, van
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3612283
g.m.van.dam@chir.umcg.nl
Department of Surgery / BioOptical Imaging Center Groningen <br>
G.M. Dam, van
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3612283
g.m.van.dam@chir.umcg.nl
Inclusion criteria
Men and women above the age of 21 who have biopsy-proven esophageal cancer that is deemed operable by the treating surgeon by the current staging protocol at the UMCG (i.e. endoscopy, endo ultrasound, CT thorax/abdomen, PET scan).
Exclusion criteria
1. Significant renal, cardiac, or pulmonary disease (ASA III-IV);
2. History of iodine allergy or anaphylactic reactions to insect bites or medication;
3. Presence or history of hyperthyroidism.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1889 |
| NTR-old | NTR2003 |
| Other | UMCG : BICG08UMCG-NIRF |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |