No registrations found.
ID
Source
Brief title
Health condition
1. Total Hip Replacement (NLD: Totale Heup Prothese);
2. Psoas Compartment Block;
3. Sciatic Nerve Block (NLD: Nervus Ischiadicus Blokkade).
Sponsors and support
Intervention
Outcome measures
Primary outcome
Pain (Visual Analog Scale) op T = 4,8,12,24,48 hour post - puncture.
Secondary outcome
1. Degree of motor block (Modified Bromage Scale).op T = 4,8,12,24,48 hour post - puncture;
2. Degree of sensory block (Loss of pin-prick sensation in leg dermatomes) op T = 4,8,12,24,48 hour post - puncture.
Background summary
Aim of our study is to compare postoperative analgesic efficacy, and the extent of sensory and motor blockade of levobupivacaine, ropivacaine and bupivacaine administered in a combined psoas compartment – sciatic nerve block (PCSNB) for total hip replacement.
45 patients undergoing total hip replacement under general anesthesia combined with PCSNB, were randomly assigned to receive either 50 cc levobupivacaine 3 mg/ml, 50 cc ropivacaine 4.5 mg/ml or 50 cc bupivacaine 3 mg/ml with epinephrine. Postoperative, the pain intensity at rest (VAS), the degree of motor block (modified Bromage Scale) and the extent of sensory block (pin prick test) will be recorded at 4, 8, 12, 24 and 48 hours following initial injection in a double blind fashion.
Study objective
Psoas Compartment - Sciatic Nerve Block, as an adjuvant locoregional anesthetic technique, gives sufficient post operative pain reduction after total hip replacement, regardless which long acting local anesthetic ((levo)bupivacaine or ropivacaine in equipotent dosages) is used.
Study design
N/A
Intervention
Psoas Compartment - Sciatic Nerve Block given with Bupivacaine, Levobupivacaine or Ropivacaine. Duration of the intervention: 10 min.
postbus 7057
Roberto S.G.M. Perez
Amsterdam 1007 MB
The Netherlands
+31 20-4440029.
rsgm.perez@vumc.nl
postbus 7057
Roberto S.G.M. Perez
Amsterdam 1007 MB
The Netherlands
+31 20-4440029.
rsgm.perez@vumc.nl
Inclusion criteria
1. Age above 18;
2. ASA classification I-III;
3. Total Hip Replacement under general anesthesia.
Exclusion criteria
1. Co-agulation disorders;
2. Infections at puncture sites;
3. Known allergy to local anesthetics;
4. Pre-existing neurological dysfunction;
5. Not been able to proper communication.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL964 |
| NTR-old | NTR990 |
| Other | : |
| ISRCTN | ISRCTN16416351 |