No registrations found.
ID
Source
Brief title
Health condition
Osteogenesis Imperfecta type I and IV.
Sponsors and support
KB 02.056.0
Lundlaan 6
3584 EA
P.O. box 85090
3508 AB Utrecht
Tel +32302504030
Fax +32302505333
m.vanbrussel@umcutrecht.nl
Intervention
Outcome measures
Primary outcome
Exercise capacity and muscle strength.
Secondary outcome
Health related quality of life.
Background summary
Aim of this study is to investigate if children with Osteogenesis Imperfecta between 8 and 18 years of age benefit from a graded exercise program with respect to exercise capacity, muscle strength, functional outcome and quality of life. thirthy-eight children with OI type I and IV between 8 and 18 years of age will be randomly assigned in two groups (RCT). eightteen children will be treated with a graded exercise protocol, by trained paediatric physical therapists, whereas the control group will not be treated and serve as the control group.
Study objective
Children with Osteogenesis Imperfecta type I and IV would benefit from a gradual trainingsprogram; increased exercise capacity and muscle strength could increase quality of life.
Study design
N/A
Intervention
Training program for 12 weeks (2 times/ week).
P.O. box 85090
R.H.H. Engelbert
Lundlaan 6
Utrecht 3508 AB
The Netherlands
+31 (0)30 2504030
r.engelbert@umcutrecht.nl
P.O. box 85090
R.H.H. Engelbert
Lundlaan 6
Utrecht 3508 AB
The Netherlands
+31 (0)30 2504030
r.engelbert@umcutrecht.nl
Inclusion criteria
1. Osteogenesis Imperfecta Type I and IV;
2. between 8 and 18 years of age;
3. ambulantory.
Exclusion criteria
1. Osteogenesis Imperfecta type II and III;
2. retardation;
3. non-walking.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL87 |
| NTR-old | NTR118 |
| Other | : 04/331-k (METC UMCU) |
| ISRCTN | ISRCTN28577651 |
Summary results
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2. Takken T, Terlingen HC, Helders PJ, Pruijs H, Van der Ent CK, Engelbert RH. Cardiopulmonary fitness and muscle strength in patients with osteogenesis imperfecta type I.J Pediatr. 2004 Dec;145(6):813-8.<br>