No registrations found.
ID
Source
Brief title
Health condition
Stabilising group therapy vs treatment as usual
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. CAPS and Davidson Trauma Scale (severity of PTSD symptoms);
2. SCID-DESNOS (overall severity of complex PTSD symptoms);
3. Borderline Personality Disorder Severity Index (BPDSI) (severity of affect-dysregulation and selfdestructiveness);
4. Dissociative Experiences Scale (DES).
Secondary outcome
1. SE (Self Esteem measure);
2. SDQ (somatic dissociation);
3. WHO- QoL (Quality of Life);
4. SCL-90 (comorbid psychopathology);
5. BDI (depression);
6. STAI (anxiety).
Background summary
The aim of this randomised controlled trial is to improve and implement outpatient treatment for severely traumatized women with ‘PTSD with associated features’ in terms of DSM-IV-TR. Especially after interpersonal traumatization in childhood PTSD - re-experiencing, numbing and hyper arousal - is complicated by personality changes such as affect dysregulation, memory disturbances, dissociation, disturbances of self-image, somatization and relational problems. This chronic syndrome is called 'PTSD with enduring personality change' in ICD-10, ‘complex PTSD’ or 'disorders of extreme stress NOS'. It is associated with severe psychiatric symptoms, high morbidity, social maladjustment and tends to run a chronic course in spite of considerable use of medical and psychiatric services. Regular PTSD exposure treatment does not lead to improvement and recent Dutch research showes a lack of adequate treatment. There is some evidence that stabilising group therapy is the most effective treatment with psycho-education and a cognitive behavioural training as techniques.
In this multicenter trial the first aim is to study the effectiveness of a 20 weekly stabilising group therapy based on Zlotnick as supplement to treatment as usual compared to TAU alone. Criteria (core symptoms) will be symptoms of C-PTSD (see above). The second aim is to identify prognostic variables: hypothesis is that the severity of dissociative symptoms (interfering with attention) and the severity of borderline symptoms (interfering with compliance) will affect success. Four centres of outpatient mental health care will participate. Assessments and treatment protocol have been successfully tested in a pilot study.
Study objective
The effectiveness of a 20-week stabilising group therapy in patients with complex PTSD is superior to treatment as usual.
Intervention
20-week group stabilising treatment for complex PTSD plus TAU vs TAU alone.
Department of Psychiatry / GGZ Buitenamstel <br>
A.J.L.M. Balkom, van
A.J. Ernststraat 887
Amsterdam 1081 HL
The Netherlands
+31 (0)20 7884549
vanbalkom@ggzba.nl
Department of Psychiatry / GGZ Buitenamstel <br>
A.J.L.M. Balkom, van
A.J. Ernststraat 887
Amsterdam 1081 HL
The Netherlands
+31 (0)20 7884549
vanbalkom@ggzba.nl
Inclusion criteria
Females diagnosed with Complex PTSD according to SCID-DESNOS with or without comorbid axis I or axis II disorders (see also exclusion criteria).
Exclusion criteria
Comorbid psychotic disorders, substance dependence; antisocial personality disorder or dissociative identity disorder, all diagnosed with SCID-I, SCID-D or SCID-II.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL575 |
| NTR-old | NTR631 |
| Other | : N/A |
| ISRCTN | ISRCTN00874587 |