No registrations found.
ID
Source
Brief title
Health condition
Depressive symptoms
Sponsors and support
(projectnr 80-007022-98-07502).
Intervention
Outcome measures
Primary outcome
Difference in severity of depressive symptoms (MADRS baseline - 6 months).
Secondary outcome
Differences (at 6 and 12 months) in:
1. Percentage responders to treatment;
2. Quality of life (SF-36, EQ-5D);
3. Mortality;
4. Use of (in)formal help or home care;
5. Medical consumption;
6. Cost-effectiveness;
7. Costs per QALY.
Background summary
We aim to study the effects and costs of a screening and treatment program for elderly with depressive symptoms in general practice. The design is a pragmatic cluster randomised controlled trial with the general practice as the unit of randomisation.
Elderly aged 75 years and over enlisted in general practices will be screened at baseline for depressive symptoms, measured by the Geriatric Depression Scale (GDS-15). If GDS-15 score is > 4 points intervention or usual care will be offered according to the allocated treatment to their general practice.
Study objective
A screening and stepped care treatment program for elderly with depressive symptoms in general practice will lead to significant reduction of depressive symptoms and costs in comparison to CAU.
Intervention
In the intervention practices elderly with depressive symptoms will be offered a stepped care treatment program, including 1) individual counselling by a community psychiatric nurse 2) psycho-education by a Coping with Depression group course or a similar therapy on individual basis, and 3) pharmacological treatment and/or referral for patients with persistence of depressive symptoms after step 1 and 2.
In the control practices elderly will receive care as usual.
P.O. Box 9600
G.M. Weele, van der
Leiden 2300 RC
The Netherlands
+31 (0)71 5268444
G.M.van_der_Weele@lumc.nl
P.O. Box 9600
G.M. Weele, van der
Leiden 2300 RC
The Netherlands
+31 (0)71 5268444
G.M.van_der_Weele@lumc.nl
Inclusion criteria
1. Inclusion criteria for screening: elderly aged 75 years and over enlisted in general practices;
2. Inclusion criteria for treatment-offer: screen positive for depression (GDS-15 > 4).
Exclusion criteria
1. Exclusion criteria for screening: terminal illness, current treatment for depression, loss of partner/important relative within previous 3 months;
2. Exclusion criteria for treatment-offer: severe cognitive impairment (MMSE < 19).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL822 |
| NTR-old | NTR835 |
| Other | : N/A |
| ISRCTN | ISRCTN71142851 |