No registrations found.
ID
Source
Brief title
Health condition
Chronic kidney disease, hypertension
Sponsors and support
Intervention
Outcome measures
Primary outcome
Suppression of sympathetic nerve activity.
Secondary outcome
The effect of statin on kidney function and PRA in hypertensive patients with CKD.
Background summary
N/A
Study objective
The central hypothesis of this proposal is that statin therapy when added to chronic ARB treatment reduces sympathetic activity. Importantly, we study the addition to ARB therapy, because that mirrors everyday clinical practice.
Study design
10 weeks.
Intervention
Statins added to ARB or ACEi.
University Medical Center Utrecht,
Department of Nephrology
Utrecht
The Netherlands
+31 (0)88 755 7379
l.siddiqi@umcutrecht.nl
University Medical Center Utrecht,
Department of Nephrology
Utrecht
The Netherlands
+31 (0)88 755 7379
l.siddiqi@umcutrecht.nl
Inclusion criteria
Patients older than 18 years old with stable chronic kidney disease and hypertension are included in this project.
Exclusion criteria
Patients with diabetes mellitus, patients on renal replacement therapy, patients on antihypertensive medication (which cannot be stopped), patients on immunosuppressive treatment are excluded.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1678 |
| NTR-old | NTR1779 |
| Other | : |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |